SCHEMBL1874653

SCHEMBL1874653

CC(C)C(C)CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)CCC(O)[C@@]45C[C@@]35CC[C@]12C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ACLY P53396 2/20 0.48
▸ ACACA Q13085 2/20 0.48
▸ PTPN11 Q06124 1/20 0.43
▸ HSD11B1 P28845 8/20 0.39
▸ HSD11B2 P80365 1/20 0.39
▸ PTGS1 P23219 1/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ EP300 Q09472 1/20 0.36
▸ EBP Q15125 4/20 0.36
▸ ESR2 Q92731 1/20 0.35
▸ CYP2C19 P33261 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ PRKAG1 P54619 1/20 0.32
▸ PRKAA2 P54646 1/20 0.32
▸ PRKAB1 Q9Y478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL568813 0.86 HSD11B1 (0.50) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL17599781 0.85 HSD11B1 (0.56) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1878450 0.85 HSD11B1 (0.56) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL16411312 0.85 ACLY (0.61) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL9618055 0.84 CRYAB (0.46) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL29510985 0.83 ACLY (0.67) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL12634185 0.83 ACLY (0.67) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL377472 0.74 ACLY (0.38) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL8148952 0.73 EBP (0.48) ACLYACACAPTPN11HSD11B1PTGS1
SCHEMBL29511134 0.72 ACLY (0.45) ACLYACACAPTPN11HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61118318-A — — None — — JP disclosed
JP-61118323-A — — None — — JP disclosed
EP-4025676-B1 PRODUCTION OF AN EXTRACT OF PHYTOSTEROLS AND STANOLS FROM TALL OIL PITCH PINE CHEMICAL HOLDING S A (LU) 2023-08-02 — — EP disclosed
EP-4025676-A1 PRODUCTION OF AN EXTRACT OF PHYTOSTEROLS AND STANOLS FROM TALL OIL PITCH BIO CHEMICAL LUXEMBOURG HOLDING S.A. (LU) 2022-07-13 — — EP disclosed
WO-2021043845-A1 PRODUCTION OF AN EXTRACT OF PHYTOSTEROLS AND STANOLS FROM TALL OIL PITCH BIO CHEMICAL LUXEMBOURG HOLDING S.A. (LU) 2021-03-11 — — WO disclosed
EP-2656737-B1 FAT AND/OR OIL COMPOSITION KAO CORP (JP) 2019-04-24 — — EP disclosed
EP-1882472-B1 DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS MORINAGA MILK INDUSTRY CO LTD (JP) 2018-08-22 — — EP disclosed
EP-1930014-B1 AGENT FOR AMELIORATION OF INSULIN RESISTANCE MORINAGA MILK INDUSTRY CO LTD (JP) 2017-03-01 — — EP disclosed
EP-2749176-B1 OIL/FAT COMPOSITION KAO CORP (JP) 2016-08-10 — — EP disclosed
EP-1795200-B1 MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA MORINAGA MILK INDUSTRY CO LTD (JP) 2014-04-23 — — EP disclosed
CN-101277705-A Agent for amelioration of insulin resistance MORINAGA MILK INDUSTRY CO LTD (JP) 2008-10-01 — — CN disclosed
EP-1930014-A1 AGENT FOR AMELIORATION OF INSULIN RESISTANCE Morinaga Milk Industry Co., Ltd. (JP) 2008-06-11 — — EP disclosed
EP-1882472-A1 DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS Morinaga Milk Industry Co., Ltd. (JP) 2008-01-30 — — EP disclosed
US-20070196435-A1 Drug and food or drink for improving hyperglycemia MORINAGA MILK INDUSTRY CO., LTD. (JP) 2007-08-23 — — US disclosed
EP-1795200-A1 MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA MORINAGA MILK INDUSTRY CO., LTD. (JP) 2007-06-13 — — EP disclosed
EP-0958370-A1 TRANSGENIC PLANTS WITH MODIFIED STEROL BIOSYNTHETIC PATHWAYS MONSANTO COMPANY (US) 1999-11-24 — — EP disclosed
WO-1998045457-A1 TRANSGENIC PLANTS WITH MODIFIED STEROL BIOSYNTHETIC PATHWAYS MONSANTO COMPANY (US) 1998-10-15 — — WO disclosed
EP-0166542-B1 TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM AMANO PHARMACEUTICAL CO., LTD. (JP) 1990-08-08 — — EP disclosed
JP-S61118323-A COMPOSITION HAVING IMPROVING ACTION ON SERUM LIPID POLA CHEM IND INC 1986-06-05 — — JP disclosed
JP-S61118318-A COMPOSITION HAVING IMPROVING ACTION ON SERUM LIPID POLA CHEM IND INC 1986-06-05 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196435-A1 Drug and food or drink for improving hyperglycemia GPR119, SLC2A9, GCKR ACLY 565/4885ACACA 305/4885PTPN11 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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