Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641080 | 0.90 | LMNA (0.47) | HSP90AA1CNR1ALDH1A1LMNAMEN1 | |
| SCHEMBL1641394 | 0.90 | CNR1 (0.53) | HSP90AA1CNR1ALDH1A1HPGDHTT | |
| SCHEMBL1640326 | 0.90 | HSP90AA1 (0.58) | HSP90AA1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL1642234 | 0.87 | WDR5 (0.46) | CNR1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL1642209 | 0.83 | EGLN1 (0.53) | HSP90AA1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL1640586 | 0.83 | TSHR (0.50) | CNR1ALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL1641018 | 0.81 | CNR1 (0.49) | CNR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1640573 | 0.81 | BRD4 (0.65) | ALDH1A1HPGDHTTLMNAMAPT | |
| SCHEMBL1642162 | 0.80 | LMNA (0.43) | HSP90AA1CNR1HPGDLMNACNR2 | |
| SCHEMBL1642389 | 0.79 | EGLN1 (0.48) | ALDH1A1HTTEGLN3SMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | HSP90AA1 789/4885CNR1 2636/4885ALDH1A1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.