Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642234 | 0.90 | WDR5 (0.46) | LMNAHPGDWDR5CCR1P2RX1 | |
| SCHEMBL1641018 | 0.87 | CNR1 (0.49) | HPGDWDR5KLKB1CNR1CNR2 | |
| SCHEMBL1642642 | 0.82 | EGLN3 (0.56) | LMNAHPGDPTGER4WDR5CCR1 | |
| SCHEMBL1641080 | 0.81 | LMNA (0.47) | LMNANPC1CNR1CNR2HSP90AA1 | |
| SCHEMBL1641375 | 0.80 | HSP90AA1 (0.53) | LMNAHPGDCNR1CNR2HSP90AA1 | |
| SCHEMBL1641394 | 0.79 | CNR1 (0.53) | LMNAHPGDCNR1CNR2HSP90AA1 | |
| SCHEMBL1641956 | 0.77 | KDM4E (0.47) | PPARGPPARDPPARA | |
| SCHEMBL1640571 | 0.75 | TDP1 (0.46) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL1640586 | 0.74 | TSHR (0.50) | LMNAHPGDCNR1CNR2 | |
| SCHEMBL1642095 | 0.71 | EGLN3 (0.66) | LMNAHPGDWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | LMNA 3462/4885HPGD 31/4885PTGER4 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.