Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16413800 | 0.87 | KDM1A (0.40) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL15325414 | 0.74 | DDB1 (0.49) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25248764 | 0.71 | KDM1A (0.40) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL3733424 | 0.70 | KDM1A (0.42) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL20456330 | 0.69 | KDM1A (0.43) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL479856 | 0.69 | KDM1A (0.43) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL27737551 | 0.68 | KDM1A (0.50) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL27192628 | 0.68 | KDM1A (0.42) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL19839783 | 0.67 | KDM1A (0.42) | KDM1AUSP30PDE4APDE4BPDE4C | |
| SCHEMBL27608489 | 0.67 | GPR119 (0.54) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031670-A1 | CYCLIC AMIDES AS METAP-2 INHIBITORS | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031670-A1 | CYCLIC AMIDES AS METAP-2 INHIBITORS | METAP2, METAP1, ENPEP | KDM1A 1924/4885USP30 2646/4885PDE4A 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.