Ethylparaben

Ethylparaben

SCHEMBL16416596

CCOC(=O)c1ccc(O)cc1.O=C1NS(=O)(=O)c2ccccc21.[NaH]

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.56
CA2 P00918 4/20 0.56
CA9 Q16790 4/20 0.56
CA1 P00915 3/20 0.56
CA7 P43166 3/20 0.56
CA14 Q9ULX7 3/20 0.56
ESR1 P03372 2/20 0.56
ESR2 Q92731 1/20 0.56
LMNA P02545 3/20 0.54
KDM4E B2RXH2 1/20 0.54
USP2 O75604 1/20 0.54
BCHE P06276 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
KMT2A Q03164 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
MAPT P10636 2/20 0.51
ALDH1A1 P00352 3/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylparaben SCHEMBL5124955 0.91 ESR1 (0.54) CA12CA2CA9CA1CA7
Butylparaben SCHEMBL20502634 0.89 ESR1 (0.52) CA12CA2CA9CA1CA7
Saccharin SCHEMBL29283763 0.80 CA12 (0.65) CA12CA2CA9CA1CA7
SCHEMBL7280576 0.80 CA12 (0.53) CA12CA2CA9CA1CA7
Saccharin SCHEMBL27496305 0.80 CA12 (0.65) CA12CA2CA9CA1CA7
Saccharin SCHEMBL10384131 0.79 CA12 (0.63) CA12CA2CA9CA1CA7
Saccharin SCHEMBL29270979 0.79 CA12 (0.67) CA12CA2CA9CA1CA7
Saccharin SCHEMBL5675345 0.78 CA12 (0.76) CA12CA2CA9CA1CA7
Saccharin SCHEMBL27538830 0.78 CA12 (0.81) CA12CA2CA9CA1CA7
SCHEMBL8001834 0.78 HSD11B1 (0.55) CA12CA2CA9CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086751-A1 STABILIZED STANNOUS COMPOSITIONS The University Of Melbourne (AU) 2016-11-02 EP disclosed
EP-3024428-A1 COMPOSITIONS AND METHODS FOR DENTAL MINERALIZATION The University of Melbourne (AU) 2016-06-01 EP disclosed
WO-2015095932-A1 STABILIZED STANNOUS COMPOSITIONS THE UNIVERSITY OF MELBOURNE (AU) 2015-07-02 WO disclosed
WO-2015010166-A1 COMPOSITIONS AND METHODS FOR DENTAL MINERALIZATION THE UNIVERSITY OF MELBOURNE (AU) 2015-01-29 WO disclosed