SCHEMBL16419858

SCHEMBL16419858

CCCCCCCCCCCCCCCC(=O)OC(COC(=O)C(C)CCCCCCCCCCCCC)COP(=O)(O)OCCNC(=O)CCCCC1SC[C@@H]2NC(=O)N[C@H]12

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 2/20 0.59
▸ CNR1 P21554 3/20 0.55
▸ F2 P00734 1/20 0.52
▸ PRSS1 P07477 1/20 0.52
▸ PRSS2 P07478 1/20 0.52
▸ PRSS3 P35030 1/20 0.52
▸ TPSAB1 Q15661 1/20 0.52
▸ PLCD1 P51178 1/20 0.51
▸ TDP1 Q9NUW8 2/20 0.46
▸ NAPEPLD Q6IQ20 1/20 0.45
▸ FOLH1 Q04609 2/20 0.44
▸ TLR2 O60603 2/20 0.43
▸ HLCS P50747 2/20 0.43
▸ FABP3 P05413 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ HPSE Q9Y251 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30165784 0.94 CNR2 (0.66) CNR2CNR1F2PRSS1PRSS2
SCHEMBL10140249 0.94 CNR2 (0.66) CNR2CNR1F2PRSS1PRSS2
SCHEMBL12989865 0.92 CNR2 (0.68) CNR2CNR1F2PRSS1PRSS2
SCHEMBL29688513 0.88 CNR2 (0.78) CNR2CNR1F2PRSS1PRSS2
SCHEMBL28660549 0.88 CNR2 (0.59) CNR2CNR1F2PRSS1PRSS2
SCHEMBL12582940 0.87 CNR2 (0.66) CNR2CNR1F2PRSS1PRSS2
SCHEMBL15746589 0.86 CNR1 (0.64) CNR2CNR1F2PRSS1PRSS2
SCHEMBL29758823 0.85 CNR2 (0.64) CNR2CNR1F2PRSS1PRSS2
SCHEMBL29910364 0.84 CNR2 (0.73) CNR2CNR1F2PRSS1PRSS2
SCHEMBL29700479 0.84 CNR2 (0.67) CNR2CNR1F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034372-B2 Lipid construct for delivery of insulin to a mammal SDG, INC. (US) 2015-05-19 — — US disclosed
US-20150031608-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. 2015-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031608-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL INSR, IAPP, GPR119 CNR2 1119/4885CNR1 719/4885F2 2597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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