Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | ACP1 | P24666 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.63 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.63 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.61 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384180 | 0.87 | ESR1 (0.64) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL13176882 | 0.87 | ESR1 (0.64) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL43880 | 0.87 | ESR1 (0.64) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Ammonia Solution, Strong SCHEMBL31241292 | 0.86 | ESR1 (0.63) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Pyridoxamine Phosphate Anhydrous SCHEMBL29619879 | 0.86 | ESR1 (0.63) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Pyridoxamine Phosphate Anhydrous SCHEMBL43832 | 0.86 | ESR1 (0.63) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Water SCHEMBL371432 | 0.86 | ESR1 (0.63) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Hydrochloric Acid SCHEMBL14331173 | 0.86 | ESR1 (0.63) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Pyridoxamine Phosphate Anhydrous SCHEMBL10942609 | 0.84 | ESR1 (0.61) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL140749 | 0.84 | HPGD (0.61) | ESR1PTGS1ACP1PDE4AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872925-B2 | Vitamin B6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy | SNU R&DB FOUNDATION (KR) | 2018-01-23 | — | — | US | disclosed |
| US-20170246309-A1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER GENE TRANSPORTER AND USE THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2017-08-31 | — | — | US | disclosed |
| US-20150030854-A1 | VITAMIN B6-COUPLED POLY(ESTER AMINE) AS GENE CARRIER AND APPLICATION IN CANCER GENE THERAPY | SNU R&DB FOUNDATION (KR) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246309-A1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER GENE TRANSPORTER AND USE THEREOF | SLC22A3, SLC22A12, SLC22A11 | ESR1 4564/4885PTGS1 2771/4885ACP1 2398/4885 |
| US-20150030854-A1 | VITAMIN B6-COUPLED POLY(ESTER AMINE) AS GENE CARRIER AND APPLICATION IN CANCER GENE THERAPY | SLC19A2, SLC19A1, VNN1 | ESR1 1658/4885PTGS1 882/4885ACP1 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.