Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879739 | 0.86 | MEN1 (0.36) | MEN1KMT2ANAAACASP2FAAH | |
| SCHEMBL2566015 | 0.85 | EPHX1 (0.42) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL16422335 | 0.83 | TSHR (0.37) | MEN1KMT2ANAAACASP2FAAH | |
| SCHEMBL28407209 | 0.83 | KDM4E (0.45) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL1023261 | 0.82 | TSHR (0.32) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL20702308 | 0.80 | EPHX1 (0.46) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL16422362 | 0.79 | MEN1 (0.45) | MEN1KMT2ANAAATSHRCA12 | |
| SCHEMBL16422284 | 0.78 | EPHX1 (0.33) | MEN1KMT2A | |
| SCHEMBL2558407 | 0.77 | — | — | |
| SCHEMBL29169990 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027628-B1 | HYDROXYMETHYLCARBOXAMIDO-SUBSTITUTED SILANOLE FOR HARDENABLE SILANE-TERMINATING POLYMERS | SIKA TECH AG (CH) | 2020-07-15 | — | — | EP | claimed |
| US-9850260-B2 | Hydroxymethyl-carboxamido-substituted silane and its use for curable, silane-terminated polymers | SIKA TECHNOLOGY AG (CH) | 2017-12-26 | — | — | US | claimed |
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2016-06-09 | — | — | US | claimed |
| EP-3027628-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS | Sika Technology AG (CH) | 2016-06-08 | — | — | EP | claimed |
| WO-2015014726-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2015-02-05 | — | — | WO | claimed |
| EP-2832735-A1 | Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | claimed |
| EP-3027666-B1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECH AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3027628-B1 | HYDROXYMETHYLCARBOXAMIDO-SUBSTITUTED SILANOLE FOR HARDENABLE SILANE-TERMINATING POLYMERS | SIKA TECH AG (CH) | 2020-07-15 | — | — | EP | disclosed |
| CN-105408337-B | Hydroxymethyl carboxamido substituted silanols for curable silane terminated polymers | SIKA技术股份公司 | 2020-03-24 | — | — | CN | disclosed |
| US-9850260-B2 | Hydroxymethyl-carboxamido-substituted silane and its use for curable, silane-terminated polymers | SIKA TECHNOLOGY AG (CH) | 2017-12-26 | — | — | US | disclosed |
| US-9790315-B2 | Polymer containing silane groups | SIKA TECHNOLOGY AG (CH) | 2017-10-17 | — | — | US | disclosed |
| US-20160369036-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-12-22 | — | — | US | disclosed |
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2016-06-09 | — | — | US | disclosed |
| EP-3027666-A1 | POLYMER CONTAINING SILANE GROUPS | Sika Technology AG (CH) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014725-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2015-02-05 | — | — | WO | disclosed |
| EP-2832735-A1 | Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | disclosed |
| EP-2832757-A1 | Polymer containing silane groups | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | BHMT2, CARM1, EHMT1 | MEN1 1136/4885KMT2A 337/4885NAAA 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.