SCHEMBL16422362

SCHEMBL16422362

CCOC(OCC)[SiH2]CCCNC(=O)C(C)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TSHR P16473 4/20 0.35
USP2 O75604 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.32
DPP7 Q9UHL4 2/20 0.32
MMP8 P22894 1/20 0.31
PTGS1 P23219 1/20 0.31
KCNH2 Q12809 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ALDH1A2 O94788 1/20 0.31
ALDH2 P05091 1/20 0.31
ALDH1A3 P47895 1/20 0.31
GAA P10253 1/20 0.31
NAAA Q02083 2/20 0.31
BRD4 O60885 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16422436 0.84 KMT2A (0.47) MEN1KMT2ATSHRUSP2DPP7
SCHEMBL2566015 0.83 EPHX1 (0.42) MEN1KMT2ATSHRGAACA12
SCHEMBL28407209 0.82 KDM4E (0.45) MEN1KMT2ATSHRL3MBTL1ALDH1A1
SCHEMBL1023261 0.81 TSHR (0.32) MEN1KMT2ATSHRL3MBTL1DPP7
SCHEMBL16422221 0.79 MEN1 (0.37) MEN1KMT2ATSHRL3MBTL1NAAA
SCHEMBL20702308 0.79 EPHX1 (0.46) MEN1KMT2ATSHRGAACA12
SCHEMBL4879739 0.78 MEN1 (0.36) MEN1KMT2ATSHRNAAACA12
SCHEMBL16422284 0.77 EPHX1 (0.33) MEN1KMT2AALDH1A1GAABRD4
SCHEMBL2558407 0.76
SCHEMBL29169990 0.75 ALDH1A1 (0.49) MEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3027628-B1 HYDROXYMETHYLCARBOXAMIDO-SUBSTITUTED SILANOLE FOR HARDENABLE SILANE-TERMINATING POLYMERS SIKA TECH AG (CH) 2020-07-15 EP claimed
CN-105408337-B Hydroxymethyl carboxamido substituted silanols for curable silane terminated polymers SIKA技术股份公司 2020-03-24 CN claimed
US-9850260-B2 Hydroxymethyl-carboxamido-substituted silane and its use for curable, silane-terminated polymers SIKA TECHNOLOGY AG (CH) 2017-12-26 US claimed
US-20160159833-A1 HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS SIKA TECHNOLOGY AG (CH) 2016-06-09 US claimed
EP-3027628-A1 HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS Sika Technology AG (CH) 2016-06-08 EP claimed
CN-105408337-A Hydroxymethyl carboxamido substituted silanols for curable silane terminated polymers SIKA TECH AG 2016-03-16 CN claimed
WO-2015014726-A1 HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS SIKA TECHNOLOGY AG (CH) 2015-02-05 WO claimed
EP-2832735-A1 Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers Sika Technology AG (CH) 2015-02-04 EP claimed
US-12509580-B2 Polymer containing silane groups SIKA TECHNOLOGY AG (CH) 2025-12-30 US disclosed
EP-4613795-A1 TIN-FREE COMPOSITIONS CONTAINING SILANE-TERMINATED POLYMERS Sika Technology AG (CH) 2025-09-10 EP disclosed
EP-4588949-A1 CURABLE SILANE-TERMINATED POLYMER COMPOSITION WITH IMPROVED ADHESION ON PLASTIC SUBSTRATES Sika Technology AG (CH) 2025-07-23 EP disclosed
US-20230072857-A1 POLYMER CONTAINING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2023-03-09 US disclosed
US-20230054396-A1 SILANE GROUP-CONTAINING BRANCHED POLYMER SIKA TECHNOLOGY AG (CH) 2023-02-23 US disclosed
CN-115551910-A Polymers containing silane groups SIKA技术股份公司 2022-12-30 CN disclosed
WO-2016083309-A1 FAST-CURING COMPOSITION CONTAINING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2016-06-02 WO disclosed
CN-105408337-A Hydroxymethyl carboxamido substituted silanols for curable silane terminated polymers SIKA TECH AG 2016-03-16 CN disclosed
CN-105408380-A Polymer containing silane groups SIKA TECH AG 2016-03-16 CN disclosed
WO-2015014725-A1 POLYMER CONTAINING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2015-02-05 WO disclosed
EP-2832757-A1 Polymer containing silane groups Sika Technology AG (CH) 2015-02-04 EP disclosed
EP-2832735-A1 Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers Sika Technology AG (CH) 2015-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159833-A1 HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS BHMT2, CARM1, EHMT1 MEN1 1136/4885KMT2A 337/4885TSHR 4846/4885
US-12509580-B2 Polymer containing silane groups NCOA3, SMAD3, NCOR1 MEN1 2623/4885KMT2A 1297/4885TSHR 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.