Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180992 | 0.88 | TSHR (0.44) | TSHRMEN1KMT2APOLBNAAA | |
| SCHEMBL22174072 | 0.86 | TSHR (0.52) | TSHRMEN1KMT2APOLBNAAA | |
| SCHEMBL18164189 | 0.84 | TSHR (0.55) | TSHRMEN1KMT2APOLBNAAA | |
| SCHEMBL16477882 | 0.84 | MEN1 (0.61) | TSHRMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL16907942 | 0.83 | TSHR (0.50) | TSHRMEN1KMT2APOLBNAAA | |
| SCHEMBL9322077 | 0.82 | TSHR (0.40) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6289357 | 0.82 | TSHR (0.40) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16422336 | 0.82 | TSHR (0.40) | TSHRMEN1KMT2APOLBNAAA | |
| SCHEMBL254189 | 0.81 | EPHX1 (0.46) | TSHRMEN1KMT2APOLBEPHX1 | |
| SCHEMBL16422258 | 0.81 | MEN1 (0.42) | TSHRMEN1KMT2ANAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027628-B1 | HYDROXYMETHYLCARBOXAMIDO-SUBSTITUTED SILANOLE FOR HARDENABLE SILANE-TERMINATING POLYMERS | SIKA TECH AG (CH) | 2020-07-15 | — | — | EP | claimed |
| US-9850260-B2 | Hydroxymethyl-carboxamido-substituted silane and its use for curable, silane-terminated polymers | SIKA TECHNOLOGY AG (CH) | 2017-12-26 | — | — | US | claimed |
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2016-06-09 | — | — | US | claimed |
| EP-3027628-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS | Sika Technology AG (CH) | 2016-06-08 | — | — | EP | claimed |
| WO-2015014726-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANOL FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2015-02-05 | — | — | WO | claimed |
| EP-2832735-A1 | Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | claimed |
| EP-3027666-B1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECH AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3027628-B1 | HYDROXYMETHYLCARBOXAMIDO-SUBSTITUTED SILANOLE FOR HARDENABLE SILANE-TERMINATING POLYMERS | SIKA TECH AG (CH) | 2020-07-15 | — | — | EP | disclosed |
| CN-105408337-B | Hydroxymethyl carboxamido substituted silanols for curable silane terminated polymers | SIKA技术股份公司 | 2020-03-24 | — | — | CN | disclosed |
| US-9850260-B2 | Hydroxymethyl-carboxamido-substituted silane and its use for curable, silane-terminated polymers | SIKA TECHNOLOGY AG (CH) | 2017-12-26 | — | — | US | disclosed |
| US-9790315-B2 | Polymer containing silane groups | SIKA TECHNOLOGY AG (CH) | 2017-10-17 | — | — | US | disclosed |
| US-20160369036-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-12-22 | — | — | US | disclosed |
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | SIKA TECHNOLOGY AG (CH) | 2016-06-09 | — | — | US | disclosed |
| EP-3027666-A1 | POLYMER CONTAINING SILANE GROUPS | Sika Technology AG (CH) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014725-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2015-02-05 | — | — | WO | disclosed |
| EP-2832757-A1 | Polymer containing silane groups | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | disclosed |
| EP-2832735-A1 | Hydroxymethylcarboxamido-substituted silanole for hardenable silane-terminating polymers | Sika Technology AG (CH) | 2015-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159833-A1 | HYDROXYMETHYL-CARBOXAMIDO-SUBSTITUTED SILANE AND ITS USE FOR CURABLE, SILANE-TERMINATED POLYMERS | BHMT2, CARM1, EHMT1 | TSHR 4846/4885MEN1 1136/4885KMT2A 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.