Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322077 | 0.90 | TSHR (0.40) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL22174072 | 0.89 | TSHR (0.52) | TSHRMEN1KMT2APOLBCASP2 | |
| SCHEMBL19273990 | 0.88 | TSHR (0.39) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16422261 | 0.88 | TSHR (0.41) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16477882 | 0.88 | MEN1 (0.61) | TSHRMEN1KMT2A | |
| SCHEMBL18164189 | 0.88 | TSHR (0.55) | TSHRMEN1KMT2APOLBCASP2 | |
| SCHEMBL6289357 | 0.86 | TSHR (0.40) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL254189 | 0.84 | EPHX1 (0.46) | TSHRMEN1KMT2APOLBEPHX1 | |
| SCHEMBL31074224 | 0.84 | TSHR (0.52) | TSHRPOLBALDH1A1CASP2FAAH | |
| SCHEMBL19083849 | 0.84 | CASP2 (0.58) | TSHRSMN1; SMN2CASP2FAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172157-A1 | SILANE ENDCAPPED POLYAMIDE RESINS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2016-10-27 | — | — | WO | disclosed |