Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344305 | 0.85 | RECQL (0.39) | RECQLALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8344303 | 0.84 | HTR2B (0.42) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8344437 | 0.77 | HTR2B (0.44) | RECQLALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8774866 | 0.75 | IDH2 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2AMY1A | |
| SCHEMBL4282014 | 0.75 | RECQL (0.57) | RECQLALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8348238 | 0.74 | TGFBR1 (0.53) | MEN1KMT2ASMN1; SMN2HPGDTSHR | |
| SCHEMBL8344301 | 0.72 | ADORA3 (0.55) | KDM4E | |
| SCHEMBL3824986 | 0.72 | MAPT (0.42) | MEN1KMT2ASMN1; SMN2PRKD3TGFBR1 | |
| SCHEMBL13649273 | 0.71 | FGFR4 (0.42) | RECQLALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13649274 | 0.70 | HTR2B (0.44) | ALDH1A1KMT2APRKD3TGFBR1PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097084-B1 | CARBOXAMIDE 4-[(4-PYRIDYL)AMINO] PYRIMIDINES FOR THE TREATMENT OF HEPATITIS C | JANSSEN R & D IRELAND (IE) | 2015-01-28 | — | — | EP | disclosed |