Sugi Predict

Sugi Predict / Compounds / SCHEMBL16429239

SCHEMBL16429239

SCHEMBL16429239

NCc1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 3/20 0.74
▸ CSNK2A1 P68400 2/20 0.58
▸ TAAR1 Q96RJ0 1/20 0.52
▸ ALDH1A1 P00352 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ HSD17B10 Q99714 2/20 0.48
▸ BCL2L1 Q07817 1/20 0.48
▸ HDAC1 Q13547 1/20 0.46
▸ PELI1 Q96FA3 1/20 0.45
▸ ALOX5 P09917 1/20 0.44
▸ DPP4 P27487 1/20 0.44
▸ ENPP2 Q13822 1/20 0.44
▸ HSD17B1 P14061 1/20 0.44
▸ HSD17B2 P37059 1/20 0.44
▸ LOXL2 Q9Y4K0 1/20 0.43
▸ THRA P10827 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ IDH1 O75874 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2807447 0.86 CSNK2A1 (0.65) BACE1CSNK2A1TAAR1ALDH1A1HPGD
SCHEMBL23991278 0.85 BACE1 (1.00) BACE1TAAR1ALDH1A1HPGDHSD17B10
SCHEMBL14832169 0.84 BACE1 (0.68) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL8956610 0.84 BACE1 (0.79) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL1176229 0.84 BACE1 (0.68) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL30003491 0.84 BACE1 (0.68) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL27508195 0.82 CSNK2A1 (0.69) BACE1CSNK2A1TAAR1ALOX5DPP4
SCHEMBL8956674 0.81 BACE1 (0.74) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL21612701 0.81 BACE1 (0.74) BACE1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL15224151 0.81 BACE1 (0.74) BACE1ALDH1A1HPGDHSD17B10BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109517260-A Transfer printing process for attaching rice paper to polyethylene acetate cotton layer ground mat 东莞市悠悠美居家居制造有限公司 2019-03-26 — — CN claimed
CN-108207443-A PE mulching film 东莞市正新包装制品有限公司 2018-06-29 — — CN claimed
CN-107488310-A A kind of high-impact environmental protection tubing of PE modified polyvinyl chloride and preparation method thereof 绵阳凤面科技有限公司 2017-12-19 — — CN claimed
CN-106349634-A Extrusion grade elastomer used for wire and cable of charging pile for new energy automobile 聚威工程塑料(上海)有限公司 2017-01-25 — — CN claimed
US-10799510-B2 Derivatives of 6-substituted triazolopyridazines as Rev-Erb agonists GENFIT (FR) 2020-10-13 — — US disclosed
CN-110204905-A A kind of cable polymer insulation protective case and processing technology 汤姆森电气有限公司 2019-09-06 — — CN disclosed
CN-110077061-A Intermediate film for laminated glasses and laminated glass 积水化学工业株式会社 2019-08-02 — — CN disclosed
CN-110062790-A Stabiliser compositions 巴斯夫欧洲公司 2019-07-26 — — CN disclosed
CN-110028885-A A kind of not solvent-laden high tenacity anticorrosive paint and preparation method thereof 王道前 2019-07-19 — — CN disclosed
CN-109863028-A Multilayer structure making and its purposes 株式会社可乐丽 2019-06-07 — — CN disclosed
CN-109790281-A crystalline polyester resin and flame-retardant sealing resin composition 东洋纺株式会社 2019-05-21 — — CN disclosed
CN-105658595-B Intermediate film for laminated glasses and laminated glass 积水化学工业株式会社 2019-04-12 — — CN disclosed
CN-106488949-A Adhesion promoter, curable silicone composition, and semiconductor device 道康宁东丽株式会社 2017-03-08 — — CN disclosed
US-9586963-B2 Derivatives of 6-substituted triazolopyridazines as Rev-Erb agonists GENFIT (FR) 2017-03-07 — — US disclosed
CN-102822284-B Curable resin composition, dry film using same, and printed wiring board 太阳控股株式会社 2017-02-22 — — CN disclosed
CN-106349634-A Extrusion grade elastomer used for wire and cable of charging pile for new energy automobile 聚威工程塑料(上海)有限公司 2017-01-25 — — CN disclosed
CN-106189186-A The 3D printing compound polyurethane material that a kind of Graphene is modified 佛山市高明区诚睿基科技有限公司 2016-12-07 — — CN disclosed
CN-106046755-A Polyurethane composite material for 3D (three-dimensional) printing 佛山市高明区诚睿基科技有限公司 2016-10-26 — — CN disclosed
CN-104448177-A Modified phenolic resin and preparation method and application thereof CHANGZHOU CHANGJING CHEMISTRY CO LTD 2015-03-25 — — CN disclosed
US-20150038503-A1 DERIVATIVES OF 6-SUBSTITUTED TRIAZOLOPYRIDAZINES AS REV-ERB AGONISTS GENFIT (FR) 2015-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10799510-B2 Derivatives of 6-substituted triazolopyridazines as Rev-Erb agonists NR1D1, NR1D2, PER2 BACE1 2625/4885CSNK2A1 255/4885TAAR1 285/4885
US-20150038503-A1 DERIVATIVES OF 6-SUBSTITUTED TRIAZOLOPYRIDAZINES AS REV-ERB AGONISTS NR1D1, NR1D2, PER2 BACE1 2625/4885CSNK2A1 255/4885TAAR1 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.