Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791560 | 0.86 | ACHE (0.39) | ACHEBBOX1MEN1KMT2ANFKB1 | |
| Hydrochloric Acid SCHEMBL324011 | 0.78 | ACHE (0.52) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| SCHEMBL170245 | 0.78 | ACHE (0.52) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| Hydrochloric Acid SCHEMBL2936558 | 0.78 | ACHE (0.52) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| SCHEMBL1568811 | 0.78 | ACHE (0.52) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| Hydrochloric Acid SCHEMBL718779 | 0.77 | ACHE (0.50) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| Hydrochloric Acid SCHEMBL8448319 | 0.77 | ACHE (0.50) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| SCHEMBL7762648 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6751685 | 0.74 | ACHE (0.47) | ACHEBBOX1MEN1KMT2AAPEX1 | |
| Methacrylic Acid SCHEMBL6561454 | 0.74 | ACHE (0.52) | ACHEBBOX1APEX1ENPP2APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162466-A | Sustained release formulation of carbamazepine | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2000-12-19 | — | — | US | claimed |
| EP-2440210-A2 | METHODS FOR TREATING GASTROINTESTINAL DISORDERS | Meritage Pharma, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20110097401-A1 | METHODS FOR TREATING GASTROINTESTINAL DISORDERS | MERITAGE PHARMA, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| WO-2010144865-A2 | METHODS FOR TREATING GASTROINTESTINAL DISORDERS | MERITAGE PHARMA, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100129777-A1 | KIT FOR FIXING A DENTAL RESTORATION MATERIAL ON A TOOTH SUBSTANCE | ERNST MÜHLBAUER GMBH & CO. KG (DE) | 2010-05-27 | — | — | US | disclosed |