Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.50 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568811 | 0.98 | ACHE (0.52) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL976265 | 0.92 | ACHE (0.45) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL424927 | 0.87 | CHRM5 (0.43) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL975794 | 0.85 | CHRM5 (0.41) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL324011 | 0.81 | ACHE (0.52) | ACHEAPEX1NPSR1ENPP2LMNA | |
| Hydrochloric Acid SCHEMBL2396954 | 0.80 | DNM1 (0.35) | TSHRBBOX1TDP1DNM1 | |
| Hydrochloric Acid SCHEMBL15663784 | 0.80 | ACHE (0.61) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7653709 | 0.77 | ACHE (0.64) | ACHECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL2936558 | 0.77 | ACHE (0.52) | ACHEAPEX1NPSR1ENPP2LMNA | |
| SCHEMBL1642927 | 0.77 | ACHE (0.52) | ACHEAPEX1NPSR1ENPP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362776-A1 | PRODUCTION OF PAPER AND BOARD | BASF SE (DE) | 2017-12-21 | — | — | US | claimed |
| US-20170233950-A1 | SOLIDIFYING COMPOSITION FOR PAPER AND CARDBOARD | BASF SE (DE) | 2017-08-17 | — | — | US | claimed |
| WO-2017092951-A1 | DOMAIN PARTICLES OF PESTICIDE PARTICLES EMBEDDED IN AN IONIC ACRYLATE COPOLYMER | BASF SE (DE) | 2017-06-08 | — | — | WO | claimed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| US-12473231-B2 | Hydrophobizing agent for mineral materials | PAGEL SPEZIAL-BETON GMBH & CO. KG (DE) | 2025-11-18 | — | — | US | disclosed |
| US-20250057753-A1 | SURFACE-COATED INORGANIC PARTICLES | KAO CORPORATION (JP) | 2025-02-20 | — | — | US | disclosed |
| US-20250049695-A1 | SURFACE-COATED PARTICLES | KAO CORPORATION (JP) | 2025-02-13 | — | — | US | disclosed |
| CN-119365501-A | Method for preparing water-soluble polymer used as shale encapsulating agent of drilling fluid | 巴斯夫欧洲公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2024262560-A1 | POWDER COMPOSITION | 花王株式会社 | 2024-12-26 | — | — | WO | disclosed |
| EP-4458768-A1 | SURFACE-COATED PARTICLES | Kao Corporation (JP) | 2024-11-06 | — | — | EP | disclosed |
| EP-4458767-A1 | SURFACE-COATED INORGANIC PARTICLES | Kao Corporation (JP) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023127597-A1 | SURFACE-COATED INORGANIC PARTICLES | 花王株式会社 | 2023-07-06 | — | — | WO | disclosed |
| US-20110257340-A1 | Process for Producing Water-Absorbing Polymer Particles | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
| US-8037635-B1 | Frog fishing lure system | WYATT CHRISTOPHER A | 2011-10-18 | — | — | US | disclosed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20100273897-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | GOETTSCHE REIMER | 2010-10-28 | — | — | US | disclosed |
| WO-2010081885-A2 | METHOD FOR THE PRODUCTION OF GLUTACONATE | BASF SE (DE) | 2010-07-22 | — | — | WO | disclosed |
| US-20100166985-A1 | AQUEOUS DISPERSIONS OF (METH)ACRYLIC ESTERS OF POLYMERS COMPRISING N-HYDROXYALKYLATED LACTAM UNITS AND USE OF (METH)ACRYLIC ESTERS OF POLYMERS COMPRISING N-HYDROXYALKYLATED LACTAM UNITS | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20090318605-A1 | POLYMER ADDITIVES CONTAINING PARTICLES | BASF SE (DE) | 2009-12-24 | — | — | US | disclosed |
| US-20080090886-A1 | Comprising fungicidal organic active substance with solubility in water of not more than 5 g/l at 25 degrees C./1013 mbar, and finely-divided ethylenically unsaturated polymer with particle sizes of not more than 300 nm, in which polymer particles comprise active substance; wood protection | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057753-A1 | SURFACE-COATED INORGANIC PARTICLES | PHOSPHO1, SGMS1, SGMS2 | ACHE 3347/4885CHRM2 65/4885CHRM1 79/4885 |
| US-20250049695-A1 | SURFACE-COATED PARTICLES | DRD3, F10, DCTN1 | ACHE 4270/4885CHRM2 714/4885CHRM1 760/4885 |
| US-20080090886-A1 | Comprising fungicidal organic active substance with solubility in water of not more than 5 g/l at 25 degrees C./1013 mbar, and finely-divided ethylenically unsaturated polymer with particle sizes of not more than 300 nm, in which polymer particles comprise active substance; wood protection | C1R, MGAM, CD68 | ACHE 1903/4885CHRM2 35/4885CHRM1 6/4885 |
| US-20100273897-A1 | AQUEOUS FUNGICIDAL COMPOSITION AND USE THEREOF FOR COMBATING HARMFUL MICROORGANISMS | C1R, MGAM, CHRM1 | ACHE 1305/4885CHRM2 25/4885CHRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.