Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL31163175 | 1.00 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5875324 | 1.00 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5875095 | 0.97 | TSHR (0.67) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5875109 | 0.97 | TSHR (0.67) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Piperazine SCHEMBL8581904 | 0.97 | TSHR (0.67) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL5875150 | 0.94 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL5875165 | 0.94 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL9949118 | 0.94 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hexanoate SCHEMBL5874310 | 0.88 | AKR1B1 (0.73) | LMNATSHRSLC22A6GPR84FFAR1 | |
| Succinic Acid SCHEMBL5874334 | 0.88 | LMNA (0.60) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122859-A1 | EXTENDED RELEASE MULTIPLE UNIT PELLET SYSTEM COMPOSITION AND ITS PROCESS FOR THE PREPARATION | NOKHA TRADING LLP (IN) | 2024-04-18 | — | — | US | claimed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |
| WO-2023051261-A1 | IMINE COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2023-04-06 | — | — | WO | claimed |
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | claimed |
| WO-2022172225-A1 | EXTENDED RELEASE MULTIPLE UNIT PELLET SYSTEM COMPOSITION AND ITS PROCESS FOR THE PREPARATION | LYRUS LIFE SCIENCES PVT. LTD. (IN) | 2022-08-18 | — | — | WO | claimed |
| US-20170135347-A1 | INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-05-18 | — | — | US | claimed |
| CN-106659160-A | Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method | 日产化学工业株式会社 | 2017-05-10 | — | — | CN | claimed |
| EP-2496089-B1 | AGENT FOR EXPELLING PARASITES IN HUMANS, ANIMALS OR BIRDS | MEIJS MARIA WILHELMINA (BE) | 2017-02-22 | — | — | EP | claimed |
| CN-104125774-A | Pest control composition comprising novel iminopyridine derivatives | MEIJI SEIKA PHARMA CO LTD | 2014-10-29 | — | — | CN | claimed |
| US-20140315839-A1 | PEST CONTROL COMPOSITION INCLUDING NOVEL IMINOPYRIDINE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-10-23 | — | — | US | claimed |
| US-20110263520-A1 | COMPOSITION FOR USE IN CONTROLLING HARMFUL ORGANISMS THAT CONTAINS 16-KETO ASPERGILLIMIDE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2011-10-27 | — | — | US | claimed |
| EP-2380439-A1 | COMPOSITION TO CONTROL HARMFUL ORGANISMS THAT CONTAINS 16-KETO ASPERGILLIMIDE | Meiji Seika Pharma Co., Ltd. (JP) | 2011-10-26 | — | — | EP | claimed |
| EP-1599190-A2 | CONTROLLED RELEASE MODIFYING COMPLEX AND PHARMACEUTICAL COMPOSITIONS THEREOF | Glenmark Pharmaceuticals Limited (IN) | 2005-11-30 | — | — | EP | claimed |
| US-20040185097-A1 | Controlled release modifying complex and pharmaceutical compositions thereof | GLENMARK PHARMACEUTICALS LTD. | 2004-09-23 | — | — | US | claimed |
| WO-2004066910-A2 | CONTROLLED RELEASE MODIFYING COMPLEX AND PHARMACEUTICAL COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-12 | — | — | WO | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0436642-B1 | PRE-ACTIVATED THERAPEUTIC AGENTS DERIVED FROM PHOTOACTIVE COMPOUNDS | BAYLOR RES FOUND (US) | 1995-04-26 | — | — | EP | claimed |
| EP-0348063-A1 | Thermoplastic elastomer and photosensitive resin composition based thereon, and printing plate precursor comprising the composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-12-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315839-A1 | PEST CONTROL COMPOSITION INCLUDING NOVEL IMINOPYRIDINE DERIVATIVE | API5, DDT, INTS9 | SLC6A2 4830/4885SLC6A3 4792/4885LMNA 1681/4885 |
| US-20110263520-A1 | COMPOSITION FOR USE IN CONTROLLING HARMFUL ORGANISMS THAT CONTAINS 16-KETO ASPERGILLIMIDE | MGAM, CYP51A1, AKR7A2 | SLC6A2 2511/4885SLC6A3 2051/4885LMNA 3555/4885 |
| US-20170135347-A1 | INSECTICIDAL, MITICIDAL, NEMATICIDAL, MOLLUSCICIDAL, MICROBICIDAL, OR BACTERICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST | DDT, ACHE, DRD5 | SLC6A2 4057/4885SLC6A3 3824/4885LMNA 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.