Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RORA | P35398 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255493 | 0.84 | KDM4E (0.44) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL1640536 | 0.77 | KCNQ3 (0.45) | RAB9AMAPTHTTNPC1SMN1; SMN2 | |
| SCHEMBL1127118 | 0.75 | RAB9A (0.35) | RAB9ATSHRMAPTHTTNPC1 | |
| SCHEMBL24760920 | 0.75 | ERCC5 (0.47) | RAB9ATSHRNPC1SMN1; SMN2KDM4E | |
| SCHEMBL310379 | 0.74 | MEN1 (0.41) | TLR7RAB9ATSHRNPC1SMN1; SMN2 | |
| SCHEMBL1640321 | 0.74 | MEN1 (0.40) | RAB9AMAPTHTTNPC1SMN1; SMN2 | |
| SCHEMBL309542 | 0.73 | RAB9A (0.57) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2254963 | 0.72 | CES2 (0.47) | RAB9AMAPTHTTNPC1SMN1; SMN2 | |
| SCHEMBL29751869 | 0.72 | CES2 (0.47) | RAB9AMAPTHTTNPC1SMN1; SMN2 | |
| SCHEMBL310067 | 0.72 | RAB9A (0.44) | RAB9AMAPTHTTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098296-A1 | Thiazole And Oxazole Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098296-A1 | Thiazole And Oxazole Kinase Inhibitors | PDXK, MAP3K1, MAP4K2 | RORC 569/4885TLR7 2130/4885GPBAR1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.