SCHEMBL16429754

SCHEMBL16429754

Cc1cccc(C)c1-c1cnc(N)cn1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 15/20 0.49
FEN1 P39748 15/20 0.49
NOS3 P29474 3/20 0.40
NOS2 P35228 3/20 0.40
NOS1 P29475 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107573 0.80 FEN1 (0.66) ALOX5APFEN1
SCHEMBL14988418 0.77 KEAP1 (0.50) NOS3NOS2NOS1
SCHEMBL22431434 0.74 CCR1 (0.65) NOS3NOS2NOS1
SCHEMBL16826157 0.73 KDM1A (0.50) ALOX5APFEN1
SCHEMBL24450787 0.72 NOS3 (0.46) ALOX5APFEN1NOS3NOS2NOS1
SCHEMBL1701328 0.72 KDM4E (0.44) ALOX5APFEN1
SCHEMBL11371855 0.71 NOS3 (0.50) ALOX5APFEN1NOS3NOS2NOS1
SCHEMBL16872803 0.71 NPC1 (0.41) NOS3NOS2NOS1
SCHEMBL28120798 0.71 FEN1 (0.52) ALOX5APFEN1
SCHEMBL40268 0.71 NPC1 (0.51) ALOX5APFEN1NOS3NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480177-A Luminescent diaza-, monoaza-and benzo-imidazole metal carbene complexes for use in electronic devices and methods for their preparation UDC 爱尔兰有限责任公司 2021-03-12 CN disclosed
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs UDC IRELAND LIMITED (IE) 2019-05-14 US disclosed
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs UDC IRELAND LIMITED (IE) 2019-05-14 US disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 US disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 US disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 US disclosed
EP-3027630-A1 LUMINESCENT DIAZA- MONOAZA- AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-08 EP disclosed
WO-2015014944-A1 LUMINESCENT DIAZA- MONOAZA- AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2015-02-05 WO disclosed
WO-2015014944-A1 LUMINESCENT DIAZA- MONOAZA- AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2015-02-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS OCIAD1, OCIAD2, OXA1L ALOX5AP 1732/4885FEN1 3090/4885NOS3 2523/4885
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs OCIAD1, OCIAD2, OXA1L ALOX5AP 1732/4885FEN1 3090/4885NOS3 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.