Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422110 | 0.89 | IDO1 (0.58) | KDM1ABCHEACHEIDO1METAP2 | |
| SCHEMBL23601607 | 0.81 | KDM1A (0.53) | KDM1ABCHEACHEIDO1METAP2 | |
| SCHEMBL28089605 | 0.81 | ALOX5AP (0.42) | ALDH1A1ALOX5APFEN1 | |
| SCHEMBL24636033 | 0.79 | BCHE (0.47) | KDM1ABCHEACHEIDO1METAP2 | |
| SCHEMBL21049734 | 0.79 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| SCHEMBL14988681 | 0.79 | KDM1A (0.61) | KDM1ABCHEACHEIDO1METAP2 | |
| SCHEMBL6820766 | 0.79 | HSD17B1 (0.79) | KDM1AMETAP2ATRHSD17B1HSD17B2 | |
| SCHEMBL2323103 | 0.79 | MAP4K4 (0.57) | BCHEACHEIDO1HSD17B1HSD17B2 | |
| SCHEMBL29818187 | 0.79 | MAP4K4 (0.57) | BCHEACHEIDO1HSD17B1HSD17B2 | |
| SCHEMBL5318865 | 0.79 | KDM1A (0.50) | KDM1AIDO1ATRHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-11434245-B2 | WNT pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-09-06 | — | — | US | disclosed |
| US-11434245-B2 | WNT pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-09-06 | — | — | US | disclosed |
| US-20210047336-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-02-18 | — | — | US | disclosed |
| US-20210047336-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-02-18 | — | — | US | disclosed |
| US-10870653-B2 | WNT pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-12-22 | — | — | US | disclosed |
| US-10870653-B2 | WNT pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-12-22 | — | — | US | disclosed |
| US-20190185478-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-06-20 | — | — | US | disclosed |
| US-10189842-B2 | Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-01-29 | — | — | US | disclosed |
| US-10189842-B2 | Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-01-29 | — | — | US | disclosed |
| US-20160311829-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLGY AND RESEARCH (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311829-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLGY AND RESEARCH (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311829-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLGY AND RESEARCH (SG) | 2016-10-27 | — | — | US | disclosed |
| EP-3083631-A1 | WNT PATHWAY MODULATORS | Agency For Science, Technology And Research (SG) | 2016-10-26 | — | — | EP | disclosed |
| CN-103370319-B | Novel coelenterazine substrate and using method thereof | 普罗美加公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-103443121-B | Novel coelenterazine substrates and methods of use thereof | PROMEGA CORP. (US) | 2016-04-20 | — | — | CN | disclosed |
| WO-2015094119-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015094119-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-25 | — | — | WO | disclosed |
| CN-103443121-A | Novel coelenterazine substrates and methods of use thereof | PROMEGA CORP | 2013-12-11 | — | — | CN | disclosed |
| CN-103370319-A | Novel coelenterazine substrates and methods of use | PROMEGA CORP | 2013-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311829-A1 | WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | KDM1A 3152/4885BCHE 4766/4885ACHE 4430/4885 |
| US-20190185478-A1 | WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | KDM1A 3768/4885BCHE 3270/4885ACHE 4421/4885 |
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | KDM1A 3803/4885BCHE 709/4885ACHE 337/4885 |
| US-10189842-B2 | Wnt pathway modulators | WNT1, WNT3A, WNT3 | KDM1A 3152/4885BCHE 4766/4885ACHE 4430/4885 |
| US-11434245-B2 | WNT pathway modulators | WNT1, WNT3A, WNT3 | KDM1A 4532/4885BCHE 3762/4885ACHE 4379/4885 |
| US-10870653-B2 | WNT pathway modulators | WNT1, WNT3A, WNT3 | KDM1A 4263/4885BCHE 3589/4885ACHE 3910/4885 |
| US-20210047336-A1 | WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | KDM1A 3768/4885BCHE 3270/4885ACHE 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.