Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 2/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430155 | 0.84 | KMT2A (0.77) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL16430359 | 0.82 | MEN1 (0.64) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL16430711 | 0.80 | TCF4 (0.66) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL16430813 | 0.78 | TCF4 (0.66) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL30926654 | 0.78 | TCF4 (0.69) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL27180756 | 0.78 | TCF4 (0.69) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL3720429 | 0.78 | TCF4 (0.81) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL16116951 | 0.78 | TCF4 (1.00) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL13546155 | 0.77 | TCF4 (0.80) | TCF4CTNNB1CYP19A1KMT2AMEN1 | |
| SCHEMBL12010901 | 0.76 | NPC1 (0.66) | KMT2AMEN1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016293-A1 | (BENZENESULFONYLAMINO)BENZAMIDE DERIVATIVE, AND SHIP2 INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人 富山大学 (JP) | 2015-02-05 | — | — | WO | disclosed |