Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.59 |
| ▸ | XDH | P47989 | 2/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 8/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503851 | 1.00 | MIF (0.59) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL28694077 | 0.88 | ALOX15 (0.58) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL29482685 | 0.87 | XDH (0.76) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL17938839 | 0.87 | XDH (0.76) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL28437800 | 0.87 | XDH (0.71) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL30912664 | 0.80 | ALOX12 (0.77) | MIFXDHPIK3CAALOX12ALOX15 | |
| SCHEMBL13279801 | 0.80 | ALOX12 (0.77) | MIFXDHPIK3CAALOX12ALOX15 | |
| SCHEMBL30851591 | 0.79 | ALOX15 (0.59) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL16431882 | 0.79 | ALOX15 (0.59) | MIFXDHPIK3CAPFKFB3ALOX12 | |
| SCHEMBL28705298 | 0.79 | ALOX15 (0.73) | MIFXDHPIK3CAPFKFB3ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111560000-B | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2022-04-12 | — | — | CN | claimed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| CN-111560000-B | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2022-04-12 | — | — | CN | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |