SCHEMBL16431598

SCHEMBL16431598

CCCc1cc(=O)c2c(CC(=O)O)cccc2o1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ HTR2B P41595 13/20 0.48
▸ HTR3A P46098 1/20 0.48
▸ GPR35 Q9HC97 1/20 0.46
▸ HTR2C P28335 4/20 0.43
▸ KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29884923 0.83 GPR35 (0.46) HTR2BHTR3AGPR35HTR2CKDM4E
SCHEMBL29395038 0.80 GPR35 (0.47) GPR35KDM4E
Phaeochromycin C SCHEMBL29884938 0.76 HTR2B (0.45) HTR2BHTR3AHTR2CKDM4E
SCHEMBL13718418 0.76 AR (0.51) HTR2BHTR3AHTR2CKDM4E
SCHEMBL17867272 0.74 KDM4E (0.43) HTR2BHTR3AHTR2CKDM4E
SCHEMBL3715533 0.70 PPARG (0.69) KDM4E
SCHEMBL30694898 0.70 PPARG (0.69) KDM4E
SCHEMBL11396835 0.68 GAA (0.48) KDM4E
SCHEMBL26092227 0.68 PTGDR2 (0.46) KDM4E
SCHEMBL7979172 0.68 GAA (0.51) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117025460-A Fermentation culture, separation and identification method for anti-complement natural product in streptomycete S063 陕西师范大学 2023-11-10 — — CN claimed
CN-117025460-A Fermentation culture, separation and identification method for anti-complement natural product in streptomycete S063 陕西师范大学 2023-11-10 — — CN disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 — — EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 — — WO disclosed
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