SCHEMBL16431806

SCHEMBL16431806

N=C(N)NCCCCCCCCC(=O)C(N)CCCNC(=N)N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 1/20 0.49
▸ CHRM4 P08173 1/20 0.49
▸ CHRM1 P11229 1/20 0.49
▸ DPP7 Q9UHL4 2/20 0.44
▸ MEN1 O00255 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ GNAI3 P08754 1/20 0.42
▸ GNAO1 P09471 1/20 0.42
▸ GNAI1 P63096 1/20 0.42
▸ RRM1 P23921 1/20 0.41
▸ ALOX15 P16050 1/20 0.39
▸ NPY4R P50391 5/20 0.37
▸ NPY1R P25929 4/20 0.37
▸ NPY2R P49146 3/20 0.37
▸ NPY5R Q15761 3/20 0.37
▸ OTC P00480 1/20 0.36
▸ ALDH1A2 O94788 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1690339 0.92 CHRM2 (0.45) CHRM2CHRM4CHRM1DPP7NPY4R
SCHEMBL9341172 0.88 CHRM2 (0.42) CHRM2CHRM4CHRM1DPP7MEN1
SCHEMBL13660193 0.85 DPP7 (0.50) CHRM2CHRM4CHRM1DPP7GNAI3
SCHEMBL8915540 0.85 CHRM2 (0.40) CHRM2CHRM4CHRM1DPP7MEN1
SCHEMBL23626315 0.84 DPP7 (0.61) DPP7MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL23610947 0.84 DPP7 (0.61) DPP7MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL2186467 0.83 DPP7 (0.39) CHRM2CHRM4CHRM1DPP7MEN1
SCHEMBL5872308 0.83 DPP7 (0.39) CHRM2CHRM4CHRM1DPP7MEN1
SCHEMBL19465128 0.83 DPP7 (0.39) CHRM2CHRM4CHRM1DPP7MEN1
SCHEMBL2186462 0.83 DPP7 (0.39) CHRM2CHRM4CHRM1DPP7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 — — EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 — — WO disclosed
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