Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OTC | P00480 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431806 | 0.92 | CHRM2 (0.49) | CHRM2CHRM4CHRM1PRMT1ALDH1A1 | |
| Azelaic Acid SCHEMBL14334673 | 0.89 | BHMT (0.50) | PRMT1ADRA1ABHMTOTC | |
| Azelaic Acid SCHEMBL14333631 | 0.89 | BHMT (0.50) | PRMT1ADRA1ABHMTOTC | |
| Arginine SCHEMBL2404172 | 0.88 | OTC (0.49) | PRMT1BHMTOTC | |
| Arginine SCHEMBL2404175 | 0.88 | OTC (0.49) | PRMT1BHMTOTC | |
| Arginine SCHEMBL7650333 | 0.84 | OTC (0.49) | BHMTOTC | |
| Arginine SCHEMBL7650337 | 0.84 | OTC (0.49) | BHMTOTC | |
| SCHEMBL9341172 | 0.84 | CHRM2 (0.42) | CHRM2CHRM4CHRM1NPY4RNPY1R | |
| Arginine SCHEMBL20610593 | 0.84 | GSR (0.51) | PRMT1BHMTALDH1A1OTC | |
| Arginine SCHEMBL22206726 | 0.84 | GSR (0.51) | PRMT1BHMTALDH1A1OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986529-B2 | Pharmaceutical compositions and related methods of delivery | AMRYT ENDO, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20220370622-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT PHARMACEUTICALS INC. | 2022-11-24 | — | — | US | disclosed |
| EP-3861986-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYPEPTIDES AND RELATED METHODS OF DELIVERY | Chiasma, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-3210474-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYPEPTIDES AND RELATED METHODS OF DELIVERY | CHIASMA INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3210474-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYPEPTIDES AND RELATED METHODS OF DELIVERY | Chiasma Inc. (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2343982-B1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | CHIASMA INC (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9566246-B2 | Pharmaceutical compositions and related methods of delivery | CHIASMA INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160158159-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT PHARMACEUTICALS INC. | 2016-06-09 | — | — | US | disclosed |
| US-9265812-B2 | Pharmaceutical compositions and related methods of delivery | AMRYT PHARMACEUTICALS INC. | 2016-02-23 | — | — | US | disclosed |
| US-20150031631-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | CHIASMA INC. (US) | 2015-01-29 | — | — | US | disclosed |
| US-8535695-B2 | Pharmaceutical compositions and related methods of delivery | CHIASMA INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8329198-B2 | Pharmaceutical compositions and related methods of delivery | CHIASMA INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120093886-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT PHARMACEUTICALS INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120009229-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT PHARMACEUTICALS INC. | 2012-01-12 | — | — | US | disclosed |
| US-20110257095-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT ENDO, INC. | 2011-10-20 | — | — | US | disclosed |
| US-20100105627-A1 | PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY | AMRYT ENDO, INC. | 2010-04-29 | — | — | US | disclosed |