SCHEMBL16433100

SCHEMBL16433100

O=C1CCc2cc3cccc(O)c3c(O)c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
DNMT1 P26358 1/20 0.52
CACNA1B Q00975 1/20 0.52
APBA1 Q02410 1/20 0.52
MCL1 Q07820 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
MAPT P10636 4/20 0.44
ALOX15 P16050 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
GAA P10253 3/20 0.44
CDK2 P24941 2/20 0.44
CYP3A4 P08684 2/20 0.44
THRB P10828 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17448111 0.87 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL29884623 0.77 MEN1 (0.44) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL17464268 0.73 MAPT (0.42) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL30067593 0.72 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL30067651 0.72 MAOA (0.39) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL30067322 0.72 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL668042 0.71 MAPT (0.55) ALDH1A1MEN1KMT2AMAPTALOX15
SCHEMBL17464265 0.70 PIM1 (0.50) ALDH1A1MEN1KMT2AMCL1MAPT
SCHEMBL3198 0.70 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ADNMT1CACNA1B
Anthralin SCHEMBL3796934 0.70 ALDH1A1 (0.69) ALDH1A1MEN1KMT2ADNMT1CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed