Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686650 | 0.90 | MAPT (0.58) | C5AR1L3MBTL1MAPTRAB9AATM | |
| SCHEMBL12584881 | 0.87 | KDM4E (0.57) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL17367260 | 0.86 | L3MBTL1 (0.51) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL18715976 | 0.85 | L3MBTL1 (0.52) | HTR1AADRA1DADRA1AADRA1BC5AR1 | |
| SCHEMBL13433963 | 0.85 | L3MBTL1 (0.52) | HTR1AADRA1DADRA1AADRA1BC5AR1 | |
| SCHEMBL15922822 | 0.85 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL3032513 | 0.85 | MAPT (0.54) | L3MBTL1MAPTRAB9AATMTDP1 | |
| SCHEMBL10801528 | 0.84 | C5AR1 (0.52) | HTR1AADRA1DADRA1AADRA1BC5AR1 | |
| SCHEMBL827943 | 0.82 | SMPD1 (0.57) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL171847 | 0.82 | NPC1 (0.58) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45364-E1 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |