SCHEMBL12584881

SCHEMBL12584881

CCOc1ccc(C)cc1OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.57
LMNA P02545 1/20 0.57
HTR1A P08908 2/20 0.56
ADRA1D P25100 2/20 0.56
ADRA1A P35348 2/20 0.56
ADRA1B P35368 2/20 0.56
ATM Q13315 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 5/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
RAB9A P51151 1/20 0.55
GAA P10253 2/20 0.55
MRGPRX4 Q96LA9 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 3/20 0.52
NTSR1 P30989 2/20 0.52
HPGD P15428 2/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686650 0.93 MAPT (0.58) KDM4ELMNAATMMEN1KMT2A
SCHEMBL16433621 0.87 HTR1A (0.50) KDM4ELMNAHTR1AADRA1DADRA1A
SCHEMBL171847 0.85 NPC1 (0.58) KDM4EHTR1AADRA1DADRA1AADRA1B
SCHEMBL827943 0.85 SMPD1 (0.57) KDM4ELMNAHTR1AADRA1DADRA1A
SCHEMBL13434101 0.84 HTR1A (0.74) KDM4ELMNAHTR1AADRA1DADRA1A
SCHEMBL805356 0.84 MAPT (0.61) KDM4EATMMEN1KMT2AMAPT
SCHEMBL12251449 0.83 MEN1 (0.63) KDM4ELMNAHTR1AADRA1DADRA1A
SCHEMBL10796837 0.83 KDM4E (0.60) KDM4ELMNAHTR1AADRA1DADRA1A
SCHEMBL17367260 0.83 L3MBTL1 (0.51) KDM4EHTR1AADRA1DADRA1AADRA1B
SCHEMBL23582260 0.82 HTR1A (0.59) KDM4ELMNAHTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C KDM4E 2641/4885LMNA 1132/4885HTR1A 2551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.