Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987917 | 1.00 | GRIN2B (0.59) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL2206812 | 1.00 | GRIN2B (0.59) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL27780170 | 0.87 | MEN1 (0.51) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL27780177 | 0.87 | NOS2 (0.50) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL27780168 | 0.87 | GRIN2B (0.65) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL27780339 | 0.85 | NOS2 (0.53) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL26231961 | 0.84 | LMNA (0.53) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL22328727 | 0.84 | GRIN2B (0.46) | GRIN2BGRIN1NOS2CYP1A2CYP2D6 | |
| SCHEMBL15947206 | 0.84 | NPC1 (0.51) | GRIN2BNOS2HTTL3MBTL1NPC1 | |
| SCHEMBL5799220 | 0.84 | NPC1 (0.51) | GRIN2BNOS2HTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415488-B2 | Bidentate secondary phosphine oxide chiral ligands for use in asymmetric addition reactions | SOLVIAS AG (CH) | 2013-04-09 | — | — | US | claimed |
| US-20110098485-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | SOLVIAS AG (CH) | 2011-04-28 | — | — | US | claimed |
| JP-2011503220-A | — | — | 2011-01-27 | — | — | JP | claimed |
| EP-2212340-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | Solvias AG (CH) | 2010-08-04 | — | — | EP | claimed |
| WO-2009065783-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | SOLVIAS AG (CH) | 2009-05-28 | — | — | WO | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0912467-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000375-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1998-01-08 | — | — | WO | claimed |
| JP-11335334-A | — | — | None | — | — | JP | disclosed |
| EP-4747366-A1 | PROCESS FOR THE REDUCTION OF AROMATIC IMINES WITH NOVEL IMINE REDUCTASES (IREDS) | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| US-20250333548-A1 | COMPOSITION AND PHOTOSENSITIVE COMPOSITION | TOKYO OHKA KOGYO CO LTD (JP) | 2025-10-30 | — | — | US | disclosed |
| US-20250282900-A1 | COMPOSITION AND PHOTOSENSITIVE COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2025-09-11 | — | — | US | disclosed |
| US-20250138421-A1 | PHOTOSENSITIVE COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2025-05-01 | — | — | US | disclosed |
| US-20250060668-A1 | PHOTOSENSITIVE COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2025-02-20 | — | — | US | disclosed |
| US-5324861-A | Selective hydrogenation of olefins, ketones, imines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5292893-A | Catalytic asymmetric and non-asymmetric reduction of times and oximes using metal catalysts | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5274146-A | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0558656-A1 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0544455-A1 | Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992009545-A2 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098485-A1 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS | H1-2, PHOSPHO1, H1-0 | GRIN2B 1397/4885GRIN1 352/4885NOS2 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.