Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16434921 | 0.82 | KMT2A (0.47) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16423441 | 0.82 | POLB (0.56) | POLBKMT2AMEN1ENPP2MAPT | |
| SCHEMBL16434955 | 0.80 | SMO (0.50) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11550138 | 0.80 | POLB (0.75) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12005574 | 0.78 | POLB (1.00) | POLBKMT2AMEN1ENPP2MAPT | |
| SCHEMBL16434957 | 0.76 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16434782 | 0.76 | MAPT (0.55) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL17770462 | 0.74 | POLB (0.69) | POLBKMT2AMEN1ENPP2MAPT | |
| SCHEMBL16434979 | 0.73 | LMNA (0.41) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL16434882 | 0.72 | ALDH1A1 (0.44) | POLBKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832728-A1 | TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR | Nissan Chemical Industries, Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |