Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16534603 | 0.80 | PSEN1 (0.40) | LMNADRD4DRD5SMN1; SMN2MAPT | |
| SCHEMBL16434901 | 0.79 | LMNA (0.46) | LMNADRD4DRD5SMN1; SMN2MAPT | |
| SCHEMBL16434921 | 0.77 | KMT2A (0.47) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL16434957 | 0.76 | MAPT (0.47) | DRD4SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL16434955 | 0.74 | SMO (0.50) | DRD4MAPTKMT2AMEN1SMO | |
| SCHEMBL16434885 | 0.73 | CYP19A1 (0.43) | LMNADRD4DRD5SMN1; SMN2MAPT | |
| SCHEMBL16434909 | 0.73 | POLB (0.60) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL16434887 | 0.73 | MAPT (0.38) | LMNADRD4DRD5SMN1; SMN2MAPT | |
| SCHEMBL16434948 | 0.71 | MEN1 (0.38) | LMNADRD4DRD5SMN1; SMN2MAPT | |
| SCHEMBL16434882 | 0.70 | ALDH1A1 (0.44) | LMNADRD4SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832728-A1 | TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR | Nissan Chemical Industries, Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |