Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254266 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL12877532 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHTTLMNA | |
| SCHEMBL491248 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL17694061 | 0.81 | CPB2 (0.44) | ALDH1A1CPB2GAASIGMAR1 | |
| SCHEMBL16311761 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL15267388 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL14307503 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL3503778 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL490877 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTHTTCPB2 | |
| SCHEMBL491245 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160106869-A1 | FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF | BRACCO IMAGING S.P.A. (IT) | 2016-04-21 | — | — | US | disclosed |
| US-9259491-B2 | Class of diazepine derivative chelating agents and complexes with paramagnetic metals thereof as MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2016-02-16 | — | — | US | disclosed |
| US-20150037261-A1 | New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents | BRACCO IMAGING S.P.A. (IT) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150037261-A1 | New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents | BAZ2A, BAZ2B, BAZ1A | ALDH1A1 4327/4885KDM4E 1717/4885MAPT 1668/4885 |
| US-20160106869-A1 | FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF | LIPA, PLIN3, NPC1L1 | ALDH1A1 812/4885KDM4E 4133/4885MAPT 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.