SCHEMBL16437553

SCHEMBL16437553

c1ccc2c(c1)Cc1ccc3c(c1-2)Cc1c-3ccc2oc3ccccc3c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.36
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
MAOA P21397 2/20 0.32
CYP3A4 P08684 2/20 0.32
GLA P06280 1/20 0.32
PGAM1 P18669 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16437552 0.92 NQO1 (0.36) NQO1KDM4EALDH1A1MAPTHPGD
SCHEMBL17879504 0.85 CA1 (0.40) NQO1KDM4EALDH1A1MAPTHPGD
SCHEMBL17954610 0.85 NQO1 (0.40) NQO1KDM4EALDH1A1MAPTHPGD
SCHEMBL17431172 0.80 PGR (0.37) NQO1KDM4EALDH1A1MAPTHPGD
SCHEMBL16437551 0.74 MAP3K9 (0.44) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL16437710 0.74 CA1 (0.47) CA1CA2CA4CA6NTRK1
SCHEMBL16437554 0.73 PNMT (0.46) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL29454006 0.73 MAOA (0.43) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL29177903 0.73 PNMT (0.44) NQO1KDM4EALDH1A1MAPTHPGD
Fluorene SCHEMBL11029824 0.73 NQO1 (0.47) NQO1KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755157-B2 Organic compound and organic optoelectric device and display device CHEIL INDUSTRIES, INC. (KR) 2017-09-05 US disclosed
US-20150034914-A1 ORGANIC COMPOUND AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES, INC. (KR) 2015-02-05 US disclosed