Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16439884 | 0.87 | HPGD (0.52) | ALDH1A1MAPTGAANPSR1HTT | |
| SCHEMBL16439866 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTNPSR1HTT | |
| SCHEMBL16440029 | 0.84 | RXFP1 (0.39) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL31270491 | 0.81 | NR1H3 (0.41) | KMT2AMEN1SMN1; SMN2SIRT2HTT | |
| SCHEMBL1766977 | 0.79 | NR1H3 (0.38) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1802624 | 0.78 | ACLY (0.43) | KMT2AALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL1766484 | 0.77 | NR1H3 (0.35) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL20537372 | 0.77 | ACLY (0.42) | KMT2AALDH1A1SMN1; SMN2MAPTSIRT2 | |
| SCHEMBL16439967 | 0.77 | TP53 (0.45) | MAPTGAATP53 | |
| SCHEMBL22520814 | 0.77 | MAPT (0.37) | KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353046-B2 | Method for producing alkylated aromatic amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150065721-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2835366-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2015-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065721-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | NAT1, HAX1, AOC2 | KMT2A 450/4885MEN1 2725/4885ALDH1A1 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.