SCHEMBL1644097

SCHEMBL1644097

NS(=O)(=O)CCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.70
RECQL P46063 1/20 0.63
CA1 P00915 7/20 0.60
CA9 Q16790 4/20 0.60
CA5A P35218 2/20 0.60
CA7 P43166 3/20 0.55
CA12 O43570 3/20 0.55
CA13 Q8N1Q1 1/20 0.55
PTGES2 Q9H7Z7 1/20 0.51
CA5B Q9Y2D0 1/20 0.50
IDO1 P14902 1/20 0.50
CA4 P22748 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
BLM P54132 1/20 0.48
GFER P55789 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063879 0.98 CA2 (0.68) CA2RECQLCA1CA9CA5A
Hydrochloric Acid SCHEMBL3516882 0.98 CA2 (0.68) CA2RECQLCA1CA9CA5A
SCHEMBL27568568 0.94 CA2 (0.63) CA2RECQLCA1CA9CA5A
SCHEMBL28384264 0.92 CA2 (0.61) CA2RECQLCA1CA9CA5A
SCHEMBL1793990 0.86 CA2 (0.72) CA2RECQLCA1CA9CA5A
SCHEMBL4061411 0.85 CA2 (0.70) CA2RECQLCA1CA9CA5A
SCHEMBL3093248 0.85 CA2 (0.65) CA2CA1CA9CA5A
SCHEMBL6378860 0.83 CA2 (0.68) CA2CA1CA9CA5AMAPT
SCHEMBL1837364 0.83 CA2 (0.68) CA2CA1CA9CA5AMAPT
SCHEMBL302785 0.80 CA2 (0.69) CA2CA1CA9CA5ACA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN claimed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
WO-2024178082-A2 COMPOSITION OF OPIOID RECEPTOR MODULATOR AND MDMA FOR USE THEREOF FREEDOM BIOSCIENCES, INC. (US) 2024-08-29 WO claimed
CN-118176003-A Medicaments comprising P2X4 receptor antagonists for the prevention or treatment of nociceptive pain and/or visceral pain 日本化学药品株式会社 2024-06-11 CN claimed
CN-118019551-A Preventive or therapeutic agent for respiratory diseases 日本化学药品株式会社 2024-05-10 CN claimed
CN-115942938-A Medicine for preventing or treating irritable bowel syndrome or inflammatory bowel disease 比萨大学 2023-04-07 CN claimed
EP-4155296-A1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS Lead Discovery Center GmbH (DE) 2023-03-29 EP claimed
CN-112519349-A Heat preservation bag 泉州市信源体育用品有限公司 2021-03-19 CN claimed
CN-110452143-A A method of mildly efficiently synthesizing 1,3- disulfide derivative UNIV SOUTHWEST NATIONALITIES 2019-11-15 CN claimed
US-20080166359-A1 Methods of using MEK inhibitors EXELIXIS, INC. 2008-07-10 US claimed
EP-1871747-A2 PROCESS FOR PREPARING ROSUVASTATIN AstraZeneca UK Limited (GB) 2008-01-02 EP claimed
EP-1735284-A1 N-(1-ARYLPYRAZOL-4L)SULFONAMIDES AND THEIR USE AS PARASITICIDES Pfizer Limited (GB) 2006-12-27 EP claimed
WO-2006067456-A2 PROCESS FOR PREPARING ROSUVASTATIN ASTRAZENECA UK LIMITED (GB) 2006-06-29 WO claimed
WO-2005089515-A2 METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2005-09-29 WO claimed
WO-2005090313-A1 N-(1-ARYLPYRAZOL-4L)SULFONAMIDES AND THEIR USE AS PARASITICIDES PFIZER LIMITED (GB) 2005-09-29 WO claimed
EP-1343782-A1 PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS GLAXO GROUP LIMITED (GB) 2003-09-17 EP claimed
WO-2002059110-A1 PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS GLAXO GROUP LIMITED (GB) 2002-08-01 WO claimed
EP-0122553-B1 N-SULPHENYL-PHENETHYL SULFONAMIDE BAYER AG (DE) 1986-02-26 EP claimed
EP-0122553-A1 N-sulphenyl-phenethyl sulfonamide BAYER AG (DE) 1984-10-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166359-A1 Methods of using MEK inhibitors BRAF, NRAS, KRAS CA2 735/4885RECQL 2550/4885CA1 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.