SCHEMBL3093248

SCHEMBL3093248

NS(=O)(=O)CCCCc1ccccc1

nearest known ligand 0.88

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.65
CA1 P00915 2/20 0.54
CA9 Q16790 2/20 0.54
CA5A P35218 1/20 0.54
MAOA P21397 1/20 0.54
MAOB P27338 2/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MGLL Q99685 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6378860 0.98 CA2 (0.68) CA2CA1CA9CA5AMAOA
SCHEMBL1837364 0.98 CA2 (0.68) CA2CA1CA9CA5AMAOA
SCHEMBL1793990 0.94 CA2 (0.72) CA2CA1CA9CA5AMAOA
SCHEMBL4061411 0.92 CA2 (0.70) CA2CA1CA9CA5AMAOA
SCHEMBL1644097 0.85 CA2 (0.70) CA2CA1CA9CA5A
Hydrochloric Acid SCHEMBL3516882 0.83 CA2 (0.68) CA2CA1CA9CA5AMAOA
SCHEMBL4063879 0.83 CA2 (0.68) CA2CA1CA9CA5A
SCHEMBL10899010 0.83 CA2 (0.63) CA2MAOAMAOBMEN1KMT2A
SCHEMBL293285 0.81 MAOB (0.54) CA2MAOAMAOBMEN1KMT2A
SCHEMBL293286 0.79 MEN1 (0.53) CA2MAOAMEN1KMT2AMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148775-A POLYAMIDE COPOLYMER, TERPENE-PHENOL RESIN, PLASTICIZER DAICEL LTD. (JP) 1979-04-10 US claimed
US-20230399322-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2023-12-14 US disclosed
US-11753403-B2 EIF4E inhibitors and uses thereof PIC Therapeutics, Inc. (US) 2023-09-12 US disclosed
CN-115667384-A Multilayer structure based on recycled polyamide 阿科玛法国公司 2023-01-31 CN disclosed
EP-4011871-A2 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS Geistlich Pharma AG (CH) 2022-06-15 EP disclosed
US-10800917-B2 Reactive blends of nylon and anhydride oligomer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-13 US disclosed
US-20180327590-A1 Reactive Blends of Nylon and Anhydride Oligomer EXXONMOBIL CHEMICAL PATENTS INC. 2018-11-15 US disclosed
CN-107922362-A 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same 株式会社钟根堂 2018-04-17 CN disclosed
CN-101784520-B Novel malonic acid sulfonamide derivative and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORP 2014-07-02 CN disclosed
US-8461209-B2 Malonic acid sulfonamide derivative and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2013-06-11 US disclosed
US-4923890-A Difluoro keto compounds and their use as HLE inhibitors ICI AMERICAS INC. (US) 1990-05-08 US disclosed
US-4910190-A Containing a nitrogen containing heterocycle ring structure ICI AMERICAS INC. (US) 1990-03-20 US disclosed
US-4880780-A RESPIRATORY SYSTEM DISORDERS ICI AMERICAS INC. (US) 1989-11-14 US disclosed
US-4873221-A Difluoro peptide compounds ICI AMERICAS INC. (US) 1989-10-10 US disclosed
EP-0276101-A2 Substituted peptide derivatives ICI AMERICAS INC. (US) 1988-07-27 EP disclosed
EP-0249349-A1 Difluoroketo compounds ICI AMERICAS INC. (US) 1987-12-16 EP disclosed
EP-0248562-A2 Difluoro peptide compounds ZENECA INC. (US) 1987-12-09 EP disclosed
EP-0204571-A2 Selected difluoro derivatives ICI AMERICAS INC. (US) 1986-12-10 EP disclosed
EP-0189305-A2 Peptide derivatives ICI AMERICAS INC. (US) 1986-07-30 EP disclosed
US-4148775-A POLYAMIDE COPOLYMER, TERPENE-PHENOL RESIN, PLASTICIZER DAICEL LTD. (JP) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399322-A1 EIF4E INHIBITORS AND USES THEREOF EIF4E, EIF4EBP1, EIF4A1 CA2 3669/4885CA1 4317/4885CA9 4088/4885
US-11753403-B2 EIF4E inhibitors and uses thereof EIF4E, EIF4EBP1, EIF4A1 CA2 3669/4885CA1 4317/4885CA9 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.