SCHEMBL28384264

SCHEMBL28384264

C=C=C.NS(=O)(=O)CCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.61
RECQL P46063 1/20 0.55
CA1 P00915 7/20 0.52
CA9 Q16790 4/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 3/20 0.49
CA12 O43570 3/20 0.49
CA13 Q8N1Q1 1/20 0.49
PTGES2 Q9H7Z7 1/20 0.46
CA5B Q9Y2D0 1/20 0.45
IDO1 P14902 1/20 0.44
CA4 P22748 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
BLM P54132 1/20 0.43
GFER P55789 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644097 0.92 CA2 (0.70) CA2RECQLCA1CA9CA5A
Hydrochloric Acid SCHEMBL3516882 0.90 CA2 (0.68) CA2RECQLCA1CA9CA5A
SCHEMBL4063879 0.90 CA2 (0.68) CA2RECQLCA1CA9CA5A
SCHEMBL27568568 0.86 CA2 (0.63) CA2RECQLCA1CA9CA5A
Phenylmethanesulfonamide SCHEMBL28388564 0.79 CA2 (0.83) CA2CA1CA9CA5ACA7
SCHEMBL1793990 0.79 CA2 (0.72) CA2RECQLCA1CA9CA5A
SCHEMBL4061411 0.78 CA2 (0.70) CA2RECQLCA1CA9CA5A
SCHEMBL3093248 0.78 CA2 (0.65) CA2CA1CA9CA5A
SCHEMBL6378860 0.76 CA2 (0.68) CA2CA1CA9CA5AMAPT
SCHEMBL1837364 0.76 CA2 (0.68) CA2CA1CA9CA5AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452143-B Method for mildly and efficiently synthesizing 1, 3-disulfide derivative 西南民族大学 2020-04-28 CN disclosed