Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829996 | 0.86 | TLR8 (0.52) | TLR8TLR7ELANEADORA1 | |
| SCHEMBL22448336 | 0.83 | ELANE (0.35) | CRHR1TLR8TLR7ELANEHCAR3 | |
| SCHEMBL22448323 | 0.77 | CYP3A4 (0.41) | CRHR1TLR8TLR7CYP3A4 | |
| SCHEMBL12105229 | 0.66 | SMN1; SMN2 (0.33) | TLR8TLR7ADORA2A | |
| SCHEMBL17830002 | 0.65 | TLR8 (0.42) | CRHR1TLR8TLR7 | |
| SCHEMBL22448325 | 0.64 | TLR8 (0.42) | TLR8TLR7 | |
| SCHEMBL18711461 | 0.63 | PIK3CA (0.34) | ADORA2BADORA2A | |
| SCHEMBL26173565 | 0.63 | TSHR (0.43) | CRHR1ADORA3CYP3A4 | |
| SCHEMBL17829984 | 0.63 | TLR8 (0.56) | TLR8TLR7ADORA2AADORA1 | |
| SCHEMBL18511556 | 0.63 | TLR7 (0.54) | CRHR1TLR8TLR7ADORA3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015014815-A1 | THIENO[3,2-d]PYRIMIDINES DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2015-02-05 | — | — | WO | disclosed |