Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076146 | 0.83 | KDM4E (0.54) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL31457597 | 0.81 | KDM4E (0.52) | KDM4EATML3MBTL1HDAC4CA1 | |
| SCHEMBL31302096 | 0.80 | KDM4E (0.50) | KDM4EATML3MBTL1HDAC4MAPT | |
| SCHEMBL18518066 | 0.79 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL16521581 | 0.79 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4MAPT | |
| SCHEMBL24332939 | 0.79 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4CA12 | |
| SCHEMBL22920227 | 0.79 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4MAPT | |
| SCHEMBL30813010 | 0.77 | KDM4E (0.47) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL3474146 | 0.76 | L3MBTL1 (0.50) | KDM4EATML3MBTL1HDAC4MAPT | |
| SCHEMBL21524840 | 0.75 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015014791-A1 | BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2015-02-05 | — | — | WO | disclosed |