SCHEMBL1644236

SCHEMBL1644236

C=CC(=O)OC(CC)(N=C=O)OC(=O)C=C

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.37
TSHR P16473 7/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151971 0.81 ALDH1A1 (0.46) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1852554 0.81 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1852556 0.81 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL14118047 0.76 TSHR (0.31) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8014080 0.76 TSHR (0.31) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1770458 0.75 TSHR (0.33) THRBTSHRHPGD
SCHEMBL28770306 0.74 TSHR (0.31) TSHR
SCHEMBL9502014 0.73 THRB (0.31) THRBTSHR
SCHEMBL17868577 0.72 THRB (0.45) THRBTSHRHPGDALDH1A1TP53
SCHEMBL9502026 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465886-B2 Color filter substrate for liquid crystal display devices and liquid crystal display devices TOPPAN PRINTING CO., LTD. (JP) 2013-06-18 US disclosed
US-8368851-B2 Color filter for liquid crystal display device and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2013-02-05 US disclosed
US-20110181818-A1 Color filter for liquid crystal display device and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-07-28 US disclosed
US-20110149215-A1 Color filter substrate and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-06-23 US disclosed
US-20110096273-A1 Color filter substrate for liquid crystal display devices and liquid crystal display devices TOPPAN PRINTING CO., LTD. (JP) 2011-04-28 US disclosed
EP-1812381-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO KABUSHIKI KAISHA (JP) 2007-08-01 EP disclosed
WO-2006049264-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO K.K. (JP) 2006-05-11 WO disclosed