Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644408 | 0.89 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL3192741 | 0.79 | AKR1C3 (0.60) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL11095361 | 0.79 | DTYMK (0.52) | MEN1KMT2AALDH1A1PTGS1PTGS2 | |
| SCHEMBL1645181 | 0.78 | SLC6A4 (0.75) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL1643391 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL1645182 | 0.76 | TXNRD1 (0.67) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL29484401 | 0.76 | TXNRD1 (0.67) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL4003277 | 0.76 | LMNA (0.68) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL3183966 | 0.76 | MAPT (0.72) | SLC6A2SLC6A4SLC6A3HTTKDM4E | |
| SCHEMBL2028311 | 0.75 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | SLC6A4, SLC18A2, SLC6A2 | SLC6A2 3/4885SLC6A4 1/4885SLC6A3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.