SCHEMBL16445181

SCHEMBL16445181

CC[CH]CCCCS(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.46
APP P05067 1/20 0.41
FAAH O00519 1/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
LMNA P02545 1/20 0.33
SLC6A6 P31641 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7082515 0.98 EPHX2 (0.49) EPHX2APPFAAHPTGS1PDE4A
SCHEMBL9683215 0.93 APP (0.42) EPHX2APPPTGS1PDE4ALMNA
SCHEMBL16445681 0.84 EPHX2 (0.49) EPHX2APPFAAHPTGS1PDE4A
SCHEMBL3724090 0.83
SCHEMBL10695345 0.83 EPHX2 (0.60) EPHX2FAAH
SCHEMBL27804633 0.83 EPHX2 (0.56) EPHX2APPFAAH
SCHEMBL7521234 0.81 APP (0.44) EPHX2APPPTGS1PDE4ALMNA
SCHEMBL11061814 0.80 EPHX2 (0.53) EPHX2APPFAAH
SCHEMBL28065626 0.79 APP (0.42) EPHX2APPPTGS1PDE4ALMNA
SCHEMBL8072057 0.78 EPHX2 (0.60) EPHX2FAAHPTGS1LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009151-A1 FORMULATIONS OF AZOBENZENE PHOTOREACTIVE COMPOUNDS BAYON THERAPEUTICS, INC. 2024-01-11 US disclosed
US-20230357451-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2023-11-09 US disclosed
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2023-10-24 US disclosed
US-20230255919-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2023-08-17 US disclosed
EP-3183295-B1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed
US-20230002513-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2023-01-05 US disclosed
EP-4083075-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CyDex Pharmaceuticals, Inc. (US) 2022-11-02 EP disclosed
EP-3702374-B1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CYDEX PHARMACEUTICALS INC (US) 2022-03-23 EP disclosed
US-11208500-B2 Manufacturing process for cyclodextrin derivatives CYDEX PHARMACEUTICALS, INC. (US) 2021-12-28 US disclosed
US-20210147582-A1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2021-05-20 US disclosed
US-20180318249-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN CYDEX PHARMACEUTICALS INC (US) 2018-11-08 US disclosed
US-10040872-B2 Alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2018-08-07 US disclosed
US-20180051098-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2018-02-22 US disclosed
US-20170275388-A1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-09-28 US disclosed
US-9751957-B2 Manufacturing process for cyclodextrin derivatives CYDEX PHARMACEUTICALS, INC. (US) 2017-09-05 US disclosed
US-20170158781-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-06-08 US disclosed
US-9493582-B2 Alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2016-11-15 US disclosed
US-20160009826-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2016-01-14 US disclosed
US-20150284479-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-10-08 US disclosed
US-20150045311-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180318249-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN SBDS, HBG1, CD99 EPHX2 3341/4885APP 3227/4885FAAH 4697/4885
US-20150284479-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME AGL, AGPS, MGAM EPHX2 1314/4885APP 630/4885FAAH 2198/4885
US-20170275388-A1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME ALG1, DDOST, AGPS EPHX2 439/4885APP 292/4885FAAH 1721/4885
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same AGPS, DDOST, ALG1 EPHX2 481/4885APP 377/4885FAAH 2334/4885
US-20170158781-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME AGL, AGPS, MGAM EPHX2 1314/4885APP 630/4885FAAH 2198/4885
US-20210147582-A1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME AGPS, DDOST, ALG1 EPHX2 481/4885APP 377/4885FAAH 2334/4885
US-20150045311-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME AGL, AGPS, MGAM EPHX2 1314/4885APP 630/4885FAAH 2198/4885
US-10040872-B2 Alkylated cyclodextrin compositions and processes for preparing and using the same AGL, AGPS, MGAM EPHX2 1314/4885APP 630/4885FAAH 2198/4885
US-20230255919-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN SBDS, HBG1, CD99 EPHX2 3341/4885APP 3227/4885FAAH 4697/4885
US-11208500-B2 Manufacturing process for cyclodextrin derivatives DCXR, AGL, OSTC EPHX2 2250/4885APP 152/4885FAAH 4834/4885
US-20240009151-A1 FORMULATIONS OF AZOBENZENE PHOTOREACTIVE COMPOUNDS CRY1, PDE6C, PDE6D EPHX2 2396/4885APP 954/4885FAAH 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.