SCHEMBL16447478

SCHEMBL16447478

NCCCOc1cc(OCCCN)cc(OCCCN)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.44
ODC1 P11926 1/20 0.43
AKT1 P31749 1/20 0.42
DYRK3 O43781 1/20 0.42
ROCK2 O75116 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PIM1 P11309 1/20 0.42
PRKACA P17612 1/20 0.42
RPS6KB1 P23443 1/20 0.42
CLK2 P49760 1/20 0.42
PRKX P51817 1/20 0.42
ROCK1 Q13464 1/20 0.42
DYRK1A Q13627 1/20 0.42
PRKG1 Q13976 1/20 0.42
PKN2 Q16513 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
STK17A Q9UEE5 1/20 0.42
NOS3 P29474 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16172408 0.92 CSF3R (0.40) TAAR1ODC1AKT1DYRK3ROCK2
SCHEMBL4355838 0.90 ALDH1A1 (0.48) TAAR1ODC1AKT1DYRK3ROCK2
SCHEMBL23374106 0.88 CNR1 (0.40) TAAR1NOS3NOS1NOS2
SCHEMBL18020389 0.88 PLA2G2A (0.47) HTR1BLTA4HPLA2G2A
SCHEMBL13411802 0.85 TAAR1 (0.59) TAAR1AKT1DYRK3ROCK2PRKD3
SCHEMBL12954770 0.83 SOD1 (0.39) TAAR1ODC1AKT1DYRK3ROCK2
SCHEMBL17164040 0.83 MAPT (0.53) TAAR1ODC1AKT1DYRK3ROCK2
SCHEMBL16169683 0.82 PLA2G2A (0.43) HTR1BLTA4HPLA2G2A
SCHEMBL31453946 0.82 TAAR1 (0.38) TAAR1AKT1
SCHEMBL16172062 0.82 CSF3R (0.36) TAAR1AKT1DYRK3ROCK2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060383-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-08-13 US disclosed
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-06-22 US disclosed
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-06-22 US disclosed
US-11578093-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-02-14 US disclosed
US-11578093-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-02-14 US disclosed
EP-3030683-B1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2022-03-02 EP disclosed
US-20210147465-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2021-05-20 US disclosed
US-20210147465-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2021-05-20 US disclosed
US-10800805-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2020-10-13 US disclosed
US-10800805-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2020-10-13 US disclosed
US-20160237279-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-18 US disclosed
US-20160237279-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-18 US disclosed
WO-2016126941-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-11 WO disclosed
WO-2016126941-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-11 WO disclosed
EP-3030683-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS Pacific Biosciences Of California, Inc. (US) 2016-06-15 EP disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed
WO-2015021079-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-02-12 WO disclosed
WO-2015021079-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885
US-11578093-B2 Protected fluorescent reagent compounds ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885
US-12060383-B2 Protected fluorescent reagent compounds ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885
US-10800805-B2 Protected fluorescent reagent compounds ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885
US-20210147465-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 TAAR1 4122/4885ODC1 2872/4885AKT1 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.