SCHEMBL16448277

SCHEMBL16448277

C=CCOOC=CCc1ccccc1CC=COOCC=C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
TSHR P16473 3/20 0.31
HSD17B10 Q99714 2/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021987 0.72 MEN1 (0.46) CYP3A4ALDH1A1KDM4ETSHRHSD17B10
SCHEMBL2028662 0.68 ALDH1A1 (0.49) ALDH1A1KDM4ETSHRHSD17B10HPGD
SCHEMBL29763626 0.67 GABRA1 (0.56) ALDH1A1KDM4EGABRA1GABRB2TSHR
SCHEMBL173300 0.67 GABRA1 (0.56) ALDH1A1KDM4EGABRA1GABRB2TSHR
SCHEMBL7036354 0.67 HSPA5 (0.37) CYP3A4ALDH1A1KDM4ETSHRMAPT
SCHEMBL30928731 0.67
SCHEMBL8680424 0.66 GABRA1 (0.45) ALDH1A1KDM4EGABRA1GABRB2TSHR
SCHEMBL11011645 0.65 GABRA1 (0.41) CYP3A4ALDH1A1KDM4EGABRA1GABRB2
SCHEMBL19437729 0.65 GABRA1 (0.54) ALDH1A1KDM4EGABRA1GABRB2TSHR
Phosphine SCHEMBL28908229 0.65 GABRA1 (0.54) ALDH1A1KDM4EGABRA1GABRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3030546-B1 METHOD FOR PREPARING ORGANIC PEROXIDES ARKEMA FRANCE (FR) 2017-12-27 EP disclosed
EP-3030546-A1 METHOD FOR PREPARING ORGANIC PEROXIDES Arkema France (FR) 2016-06-15 EP disclosed
WO-2015018996-A1 METHOD FOR PREPARING ORGANIC PEROXIDES ARKEMA FRANCE (FR) 2015-02-12 WO disclosed