SCHEMBL8021987

SCHEMBL8021987

C=CCOOC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
IDO1 P14902 2/20 0.41
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
MAOB P27338 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
RELA Q04206 1/20 0.35
CYP3A4 P08684 1/20 0.35
TRPA1 O75762 1/20 0.34
ALOX12 P18054 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386809 0.84 MEN1 (0.49) MEN1KMT2AIDO1ALDH1A1TSHR
SCHEMBL7770634 0.84 MEN1 (0.49) MEN1KMT2AIDO1ALDH1A1TSHR
SCHEMBL28340911 0.78 IDO1 (0.57) MEN1KMT2AIDO1ALDH1A1TSHR
SCHEMBL367481 0.76 MAOB (0.55) MEN1KMT2AIDO1ALDH1A1TSHR
SCHEMBL8008236 0.73 PAM (0.41) IDO1ALDH1A1MAOBLMNAMAPT
SCHEMBL367480 0.72 MAOB (0.50) MEN1KMT2AIDO1ALDH1A1MAOB
SCHEMBL367479 0.72 MAOB (0.50) MEN1KMT2AIDO1ALDH1A1MAOB
SCHEMBL16448277 0.72 CYP3A4 (0.34) ALDH1A1TSHRKDM4EMAPTMAPK1
SCHEMBL2086964 0.71 ALDH1A1 (0.44) MEN1KMT2AIDO1ALDH1A1TSHR
SCHEMBL1158123 0.71 IDO1 (0.57) MEN1KMT2AIDO1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6132548-A ADHESIVES AND SEALANTS WITH INCREASED VISCOSITIES AND GOOD STORAGE STABILITY PREPARED USING A CATIONICALLY CURABLE MONOMER AND A THICKENING POLYMER (THE ALKENYLATION OF POLY-4-HYDROXYSTYRENE; BONDING OF GLASS SUBSTRATES FOR FLAT PANELS LOCTITE CORPORATION (US) 2000-10-17 US disclosed
EP-0929581-A1 PROCESS FOR THE ASSEMBLY OF GLASS DEVICES SUBJECTED TO HIGH TEMPERATURES, COMPOSITIONS THEREFOR AND NOVEL POLYMERS FOR RHEOLOGICAL CONTROL OF SUCH COMPOSITIONS LOCTITE CORPORATION (US) 1999-07-21 EP disclosed
US-5902838-A CATIONICALLY CURABLE MONOMER INCLUDING AN ALKENYLOXYSTYRENE AND A THICKENING MONOMER WHICH IS THE ALKYLATION PRODUCT OF POLY(2- OR 4-HYDROXYSTRYRENE) WITH AN ALLYL, METHALLYL, CROTYL, OR PRENYL HALIDE; FLAT PANEL DISPLAY SEALANTDISPLAYS LOCTITE CORPORATION (US) 1999-05-11 US disclosed
WO-1998014487-A1 PROCESS FOR THE ASSEMBLY OF GLASS DEVICES SUBJECTED TO HIGH TEMPERATURES, COMPOSITIONS THEREFOR AND NOVEL POLYMERS FOR RHEOLOGICAL CONTROL OF SUCH COMPOSITIONS LOCTITE CORPORATION (US) 1998-04-09 WO disclosed