SCHEMBL21687635

SCHEMBL21687635

N#Cc1c(-c2ccccc2[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cccc1-n1c2ccccc2c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
ELANE P08246 1/20 0.32
DUSP3 P51452 1/20 0.32
EGFR P00533 1/20 0.32
SRC P12931 1/20 0.32
MAPK1 P28482 2/20 0.32
STAT3 P40763 1/20 0.32
NRP1 O14786 1/20 0.31
MAPT P10636 1/20 0.31
PARP1 P09874 1/20 0.31
TSHR P16473 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21687781 0.95 SMN1; SMN2 (0.37) SMN1; SMN2HIF1AALDH1A1KDM4EL3MBTL1
SCHEMBL21687778 0.92 ALDH1A1 (0.33) SMN1; SMN2HIF1AALDH1A1KDM4EL3MBTL1
SCHEMBL21687985 0.91 ALDH1A1 (0.35) SMN1; SMN2HIF1AALDH1A1KDM4EL3MBTL1
SCHEMBL21687718 0.91 PTGER4 (0.32) SMN1; SMN2HIF1AALDH1A1KDM4EGAA
SCHEMBL21688054 0.88 SMN1; SMN2 (0.33) SMN1; SMN2HIF1AALDH1A1KDM4EMAPK1
SCHEMBL21688124 0.88 SMN1; SMN2 (0.33) SMN1; SMN2HIF1AALDH1A1KDM4EEGFR
SCHEMBL21687646 0.87 METAP2 (0.33) ALDH1A1KDM4EL3MBTL1KMT2A
SCHEMBL21688012 0.87 SMN1; SMN2 (0.34) SMN1; SMN2HIF1AALDH1A1KDM4EGAA
SCHEMBL21687764 0.87 SMN1; SMN2 (0.41) SMN1; SMN2HIF1AALDH1A1KDM4ESTAT3
SCHEMBL26771765 0.84 ALDH1A1 (0.42) ALDH1A1KDM4EL3MBTL1ATMDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 SMN1; SMN2 4039/4885HIF1A 622/4885ALDH1A1 616/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 SMN1; SMN2 4039/4885HIF1A 622/4885ALDH1A1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.