Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29304439 | 0.84 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL85215 | 0.83 | OPRM1 (0.44) | OPRM1CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL16448466 | 0.83 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL13597028 | 0.82 | OPRM1 (0.51) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL13597004 | 0.81 | L3MBTL1 (0.56) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL13597009 | 0.79 | DPP4 (0.55) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL29913750 | 0.79 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL3458578 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL8473371 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 | |
| SCHEMBL8472991 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1OPRM1CYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952169-B2 | N-substituted benzamides and methods of use thereof | XENON PHARMACEUTICALS INC. (CA) | 2015-02-10 | — | — | US | disclosed |