SCHEMBL16449113

SCHEMBL16449113

CCCCCC[Si](O[SiH2]C)(O[SiH2]C)O[SiH2]C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.38
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31
DNM1 Q05193 5/20 0.31
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071644 0.79 TSHR (0.36) LMNATSHRTHRB
SCHEMBL790048 0.79 TSHR (0.36) LMNATSHRTHRB
SCHEMBL3058859 0.79 TSHR (0.36) LMNATSHRTHRB
SCHEMBL7601810 0.76 TSHR (0.32) TSHRTHRB
SCHEMBL10813558 0.76 EPHX2 (0.33) TSHRTHRB
SCHEMBL8432714 0.74 TSHR (0.41) LMNATSHRLPAR2LPAR3ALDH1A1
SCHEMBL1780545 0.72 LMNA (0.65) LMNATSHRTHRBDNM1ALDH1A1
Hexane SCHEMBL6049081 0.72 LMNA (0.65) LMNATSHRTHRBDNM1ALDH1A1
SCHEMBL17003993 0.72 LMNA (0.65) LMNATSHRTHRBDNM1ALDH1A1
SCHEMBL304612 0.72 LMNA (0.65) LMNATSHRTHRBDNM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8951611-B2 Methods and compositions for treating wood EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-02-10 US disclosed