SCHEMBL790048

SCHEMBL790048

CCCCCC[Si](C)(C)O[SiH2]C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071644 1.00 TSHR (0.36) TSHRTHRBLMNA
SCHEMBL3058859 1.00 TSHR (0.36) TSHRTHRBLMNA
SCHEMBL7601810 0.98 TSHR (0.32) TSHRTHRB
SCHEMBL28250268 0.91
SCHEMBL7781874 0.86 TSHR (0.53) TSHRLMNA
SCHEMBL5572146 0.84
SCHEMBL11763959 0.80 TSHR (0.35) TSHRTHRB
SCHEMBL16449113 0.79 LMNA (0.39) TSHRTHRBLMNA
SCHEMBL10813558 0.78 EPHX2 (0.33) TSHRTHRB
SCHEMBL28702309 0.77 TSHR (0.32) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6780402-B1 TRANSFER-RESISTANT ANHYDROUS MAKE-UP COMPOSITION IN STICK FORM CONTAINING FATTY PHASE CONSISTING OF PHENYLATED SILICONE OIL, VOLATILE OIL WITH FLASHPOINT OF 40-100 DEGREES C., HYDROCARBON AND/OR SILICONE WAX, LESS THAN 5% NON-VOLATILE HYDROCARBON OIL L'OREAL (FR) 2004-08-24 US claimed
EP-0756865-B2 Composition in form of a supple paste and preparation process OREAL (FR) 2002-01-02 EP claimed
US-6335025-B1 ALKYLPOLYGLYCOSIDE AND VOLATILE OIL; STABILITY, FRESHNESS; USED FOR SKIN, NAILS, HAIR L'OREAL (FR) 2002-01-01 US claimed
US-6136332-A NONAQUEOUS, TOPICAL SOCIETE L'OREAL S.A. (FR) 2000-10-24 US claimed
US-6080793-A MELTING PREMIX OF FIRST INGREDIENT AND SECOND INGREDIENT WHICH IS DENATURED OR VOLATILIZED AT MELTING POINT OF FIRST INGREDIENT, EXTRUDER BLENDING AND COOLING WHILE CONTINUING TO ADD SECOND INGREDIENT UNTIL ROOM TEMPERATURE IS REACHED SOCIETE L'OREAL S.A. (FR) 2000-06-27 US claimed
US-6024969-A FATTY ACIDS AND PHENYLATED SILICONE OILS WITH WAX SOCIETE L'OREAL S.A. (FR) 2000-02-15 US claimed
US-5965148-A CONTAINING FATTY PHASE OF VOLATILE OIL AND AT LEAST ONE PHENYLATED SILICONE OIL SOCIETE L'OREAL S.A. (FR) 1999-10-12 US claimed
US-5945095-A Cosmetic composition including a polymeric particle dispersion L'OREAL (FR) 1999-08-31 US claimed
US-5936002-A SUPPLE DOUGH EXTRUDATE, HEAT-SENSITIVE COMPOUND WHICH IS CAPABLE OF EVAPORATING UPON CONTACT WITH THE SKIN AND/OR HAS A FLASH POINT LOWER THAN ABOUT 100.DEGREE. C. AND AT LEAST ONE WAX HOMOGENEOUSLY DISTRIBUTED THERETHROUGH SOCIETE L'OREAL S.A. (FR) 1999-08-10 US claimed
EP-0756865-B1 Composition in form of a supple paste and preparation process OREAL (FR) 1998-06-24 EP claimed
EP-0756863-B1 Preparation process of a composition containing a heat-sensitive compound and the composition obtained thereby OREAL (FR) 1997-12-29 EP claimed
EP-0756864-B1 Use of the association of two particular oils in a cosmetic composition, and the composition obtained thereby OREAL (FR) 1997-11-26 EP claimed
EP-0755675-B1 Dermatological and/or pharmaceutical composition, process of preparation and utilization OREAL (FR) 1997-09-17 EP claimed
EP-0749746-B1 Cosmetic composition containing a dispersion of polymer particles OREAL (FR) 1997-09-03 EP claimed
EP-0756865-A1 Composition in form of a supple paste and preparation process L'OREAL (FR) 1997-02-05 EP claimed
EP-0756864-A1 Use of the association of two particular oils in a cosmetic composition, and the composition obtained thereby L'OREAL (FR) 1997-02-05 EP claimed
EP-0756863-A1 Preparation process of a composition containing a heat-sensitive compound and the composition obtained thereby L'OREAL (FR) 1997-02-05 EP claimed
EP-0755675-A1 Dermatological and/or pharmaceutical composition, process of preparation and utilization L'OREAL (FR) 1997-01-29 EP claimed
WO-1997000662-A1 COSMETIC COMPOSITION INCLUDING A POLYMERIC PARTICLE DISPERSION L'OREAL (FR) 1997-01-09 WO claimed
EP-0749746-A1 Cosmetic composition containing a dispersion of polymer particles L'OREAL (FR) 1996-12-27 EP claimed