SCHEMBL7071644

SCHEMBL7071644

CCCCCCCCCCCCCCCCCC[Si](C)(C)O[SiH2]C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL790048 1.00 TSHR (0.36) TSHRTHRBLMNA
SCHEMBL3058859 1.00 TSHR (0.36) TSHRTHRBLMNA
SCHEMBL7601810 0.98 TSHR (0.32) TSHRTHRB
SCHEMBL28250268 0.91
SCHEMBL7781874 0.86 TSHR (0.53) TSHRLMNA
SCHEMBL5572146 0.84
SCHEMBL11763959 0.80 TSHR (0.35) TSHRTHRB
SCHEMBL16449113 0.79 LMNA (0.39) TSHRTHRBLMNA
SCHEMBL10813558 0.78 EPHX2 (0.33) TSHRTHRB
SCHEMBL28702309 0.77 TSHR (0.32) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969735-B1 CHEWING GUM AND GUM BASES WITH REDUCED ADHESION TO ENVIRONMENTAL SURFACES WRIGLEY W M JUN CO (US) 2003-06-25 EP claimed
US-20020127251-A1 Cosmetic or pharmaceutical compositions comprising thermally stabilizing microcapsules L'OREAL (FR) 2002-09-12 US disclosed
EP-1201220-A1 Cosmetic or pharmaceutical compositions containing thermostabilising microcapsules L'OREAL (FR) 2002-05-02 EP disclosed