Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699575 | 0.83 | MAPT (0.52) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL27707625 | 0.82 | MAPT (0.50) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL20562670 | 0.77 | ERN1 (0.65) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL19413657 | 0.75 | LMNA (0.51) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL20564143 | 0.75 | SMN1; SMN2 (0.44) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL20564141 | 0.75 | SMN1; SMN2 (0.44) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL25464150 | 0.73 | CYP2A6 (0.47) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL21841136 | 0.73 | L3MBTL1 (0.56) | MAPTKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19041295 | 0.73 | — | — | |
| SCHEMBL14511529 | 0.73 | NFE2L2 (0.34) | MAPTKDM4EALDH1A1HSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | PDCD1, PDCD11, TYMP | MAPT 360/4885KDM4E 4423/4885ERN1 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.